Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Hsdl2 hydroxysteroid dehydrogenase like 2 [ Mus musculus (house mouse) ]

    Gene ID: 72479, updated on 23-Jun-2021

    Summary

    Official Symbol
    Hsdl2provided by MGI
    Official Full Name
    hydroxysteroid dehydrogenase like 2provided by MGI
    Primary source
    MGI:MGI:1919729
    See related
    Ensembl:ENSMUSG00000028383
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2610207I16Rik
    Expression
    Ubiquitous expression in heart adult (RPKM 26.3), bladder adult (RPKM 20.5) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Hsdl2 in Genome Data Viewer
    Location:
    4; 4 B3
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (59581515..59618694)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (59581517..59618694)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (59594435..59631566)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene sushi domain containing 1 Neighboring gene zinc finger, MYND domain containing 19 pseudogene Neighboring gene polypyrimidine tract binding protein 3 Neighboring gene RIKEN cDNA E130308A19 gene Neighboring gene high mobility group protein B1-like Neighboring gene INTS3 and NABP interacting protein

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrion HDA PubMed 
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in peroxisome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    hydroxysteroid dehydrogenase-like protein 2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001301367.1NP_001288296.1  hydroxysteroid dehydrogenase-like protein 2 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) has an additional exon in the 5' region, which causes translation initiation at a downstream in-frame start codon, compared to variant 1. The encoded protein (isoform 2) is shorter at the N-terminus than isoform 1.
      Source sequence(s)
      AL806512, BX005031
      Consensus CDS
      CCDS80104.1
      UniProtKB/TrEMBL
      B1AX78
      Related
      ENSMUSP00000103152.2, ENSMUST00000107528.8
      Conserved Domains (2) summary
      pfam02036
      Location:270363
      SCP2; SCP-2 sterol transfer family
      cl21454
      Location:1128
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    2. NM_024255.3NP_077217.2  hydroxysteroid dehydrogenase-like protein 2 isoform 1

      See identical proteins and their annotated locations for NP_077217.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the shorter transcript but encodes the longer isoform (1).
      Source sequence(s)
      AA545425, AY725196, BE944922, BY327952
      Consensus CDS
      CCDS38772.1
      UniProtKB/Swiss-Prot
      Q2TPA8
      Related
      ENSMUSP00000030078.6, ENSMUST00000030078.12
      Conserved Domains (3) summary
      cd09762
      Location:8248
      HSDL2_SDR_c; human hydroxysteroid dehydrogenase-like protein 2 (HSDL2), classical (c) SDRs
      pfam00106
      Location:12197
      adh_short; short chain dehydrogenase
      pfam02036
      Location:390483
      SCP2; SCP-2 sterol transfer family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      59581515..59618694
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036164461.1XP_036020354.1  hydroxysteroid dehydrogenase-like protein 2 isoform X3

      Conserved Domains (2) summary
      pfam02036
      Location:186278
      SCP2; SCP-2 sterol transfer family
      cl21454
      Location:369
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    2. XM_006538277.4XP_006538340.1  hydroxysteroid dehydrogenase-like protein 2 isoform X2

      Conserved Domains (2) summary
      pfam02036
      Location:358450
      SCP2; SCP-2 sterol transfer family
      cl21454
      Location:8215
      NADB_Rossmann; Rossmann-fold NAD(P)(+)-binding proteins
    3. XM_036164460.1XP_036020353.1  hydroxysteroid dehydrogenase-like protein 2 isoform X1

      Conserved Domains (2) summary
      cd09762
      Location:8248
      HSDL2_SDR_c; human hydroxysteroid dehydrogenase-like protein 2 (HSDL2), classical (c) SDRs
      pfam02036
      Location:391456
      SCP2; SCP-2 sterol transfer family
    Support Center