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    Hao1 hydroxyacid oxidase 1, liver [ Mus musculus (house mouse) ]

    Gene ID: 15112, updated on 6-May-2021

    Summary

    Official Symbol
    Hao1provided by MGI
    Official Full Name
    hydroxyacid oxidase 1, liverprovided by MGI
    Primary source
    MGI:MGI:96011
    See related
    Ensembl:ENSMUSG00000027261
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    GO; GOX; Hao; Gox1; Hao-1
    Expression
    Biased expression in liver E18 (RPKM 32.6) and liver adult (RPKM 18.0) See more
    Orthologs
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    Genomic context

    See Hao1 in Genome Data Viewer
    Location:
    2 F2; 2 65.65 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (134339281..134396272, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (134497361..134554352, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (134323097..134380088, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 39940 Neighboring gene uncharacterized LOC118568537 Neighboring gene predicted gene, 52526 Neighboring gene thioredoxin-related transmembrane protein 4 Neighboring gene predicted gene 14037

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC141211

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables (S)-2-hydroxy-acid oxidase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables (S)-2-hydroxy-acid oxidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables FMN binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables glycolate oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables glycolate oxidase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables long-chain-(S)-2-hydroxy-long-chain-acid oxidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables medium-chain-(S)-2-hydroxy-acid oxidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables very-long-chain-(S)-2-hydroxy-acid oxidase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in fatty acid alpha-oxidation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in fatty acid alpha-oxidation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in glycolate catabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in peroxisome IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in peroxisome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in peroxisome ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    hydroxyacid oxidase 1
    Names
    HAOX1
    glycolate oxidase 1
    NP_034533.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010403.2NP_034533.1  hydroxyacid oxidase 1

      See identical proteins and their annotated locations for NP_034533.1

      Status: PROVISIONAL

      Source sequence(s)
      AL845309
      Consensus CDS
      CCDS16783.1
      UniProtKB/Swiss-Prot
      Q9WU19
      UniProtKB/TrEMBL
      Q3UEE8
      Related
      ENSMUSP00000028704.3, ENSMUST00000028704.3
      Conserved Domains (2) summary
      cd02809
      Location:9357
      alpha_hydroxyacid_oxid_FMN; Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate ...
      pfam01070
      Location:16362
      FMN_dh; FMN-dependent dehydrogenase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      134339281..134396272 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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