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    Myo1g myosin IG [ Mus musculus (house mouse) ]

    Gene ID: 246177, updated on 8-Nov-2021

    Summary

    Official Symbol
    Myo1gprovided by MGI
    Official Full Name
    myosin IGprovided by MGI
    Primary source
    MGI:MGI:1927091
    See related
    Ensembl:ENSMUSG00000020437
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    E430002D17Rik
    Expression
    Biased expression in spleen adult (RPKM 76.0), thymus adult (RPKM 51.7) and 6 other tissues See more
    Orthologs
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    Genomic context

    See Myo1g in Genome Data Viewer
    Location:
    11; 11 A1
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (6456548..6470960, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (6506548..6520960, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (6406551..6420961, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S15a pseudogene Neighboring gene purine rich element binding protein B Neighboring gene small nucleolar RNA host gene 15 Neighboring gene small nucleolar RNA, H/ACA box 9 Neighboring gene predicted gene, 24000

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables actin filament binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables cytoskeletal motor activity TAS
    Traceable Author Statement
    more info
    PubMed 
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables microfilament motor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol-3,4,5-trisphosphate binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables phosphatidylinositol-3,4-bisphosphate binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables phosphatidylinositol-4,5-bisphosphate binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in actin cytoskeleton IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in filopodium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in lamellipodium IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in leading edge membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in microvillus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in microvillus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of myosin complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in phagocytic cup IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    unconventional myosin-Ig
    Names
    myosin 1G
    myosin-Ig

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178440.4NP_848534.2  unconventional myosin-Ig

      See identical proteins and their annotated locations for NP_848534.2

      Status: VALIDATED

      Source sequence(s)
      AK030825, AK152797, AK171505
      Consensus CDS
      CCDS24421.1
      UniProtKB/Swiss-Prot
      Q5SUA5
      Related
      ENSMUSP00000003459.4, ENSMUST00000003459.4
      Conserved Domains (3) summary
      smart00242
      Location:10712
      MYSc; Myosin. Large ATPases
      cd01378
      Location:29700
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:8211015
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      6456548..6470960 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006514702.1XP_006514765.1  unconventional myosin-Ig isoform X2

      Conserved Domains (2) summary
      cd01378
      Location:1606
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:727898
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding
    2. XM_006514700.1XP_006514763.1  unconventional myosin-Ig isoform X1

      Conserved Domains (2) summary
      cd01378
      Location:52715
      MYSc_Myo1; class I myosin, motor domain
      pfam06017
      Location:8361007
      Myosin_TH1; Unconventional myosin tail, actin- and lipid-binding

    RNA

    1. XR_380967.2 RNA Sequence

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