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    Lgals4 lectin, galactose binding, soluble 4 [ Mus musculus (house mouse) ]

    Gene ID: 16855, updated on 23-Jun-2021

    Summary

    Official Symbol
    Lgals4provided by MGI
    Official Full Name
    lectin, galactose binding, soluble 4provided by MGI
    Primary source
    MGI:MGI:107536
    See related
    Ensembl:ENSMUSG00000053964
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    gal-4; galect
    Expression
    Biased expression in large intestine adult (RPKM 1251.9), colon adult (RPKM 1110.2) and 3 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Lgals4 in Genome Data Viewer
    Location:
    7 B1; 7 16.94 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (28532538..28541135)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (28833122..28841710)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (29619011..29626722)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein L Neighboring gene enoyl coenzyme A hydratase 1, peroxisomal Neighboring gene lectin, galactose binding, soluble 7 Neighboring gene predicted gene 10648

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables carbohydrate binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables galactoside binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    galectin-4
    Names
    lactose-binding lectin 4

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010706.2NP_034836.1  galectin-4

      See identical proteins and their annotated locations for NP_034836.1

      Status: VALIDATED

      Source sequence(s)
      AC171210, AF510729, AK145734
      Consensus CDS
      CCDS21058.1
      UniProtKB/Swiss-Prot
      Q8K419
      UniProtKB/TrEMBL
      Q3UL35
      Related
      ENSMUSP00000066461.9, ENSMUST00000066723.15
      Conserved Domains (2) summary
      smart00908
      Location:203325
      Gal-bind_lectin; Galactoside-binding lectin
      cd00070
      Location:18147
      GLECT; Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      28532538..28541135
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539566.5XP_006539629.1  galectin-4 isoform X1

      Conserved Domains (2) summary
      smart00908
      Location:192314
      Gal-bind_lectin; Galactoside-binding lectin
      cd00070
      Location:18147
      GLECT; Galectin/galactose-binding lectin. This domain exclusively binds beta-galactosides, such as lactose, and does not require metal ions for activity. GLECT domains occur as homodimers or tandemly repeated domains. They are developmentally regulated and may ...
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