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    Gpr155 G protein-coupled receptor 155 [ Mus musculus (house mouse) ]

    Gene ID: 68526, updated on 23-Jun-2021

    Summary

    Official Symbol
    Gpr155provided by MGI
    Official Full Name
    G protein-coupled receptor 155provided by MGI
    Primary source
    MGI:MGI:1915776
    See related
    Ensembl:ENSMUSG00000041762
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    PGR; DEPDC; PGR22; DEPDC3; 1110017O10Rik; F730029F15Rik
    Expression
    Ubiquitous expression in cortex adult (RPKM 5.0), genital fat pad adult (RPKM 4.7) and 27 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Gpr155 in Genome Data Viewer
    Location:
    2; 2 C3
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (73171850..73216842, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (73341506..73386521, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (73179564..73224455, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene corepressor interacting with RBPJ, 1 Neighboring gene secernin 3 Neighboring gene predicted gene 13709 Neighboring gene predicted gene 13707 Neighboring gene WAS/WASL interacting protein family, member 1 Neighboring gene predicted gene, 54162

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

    Markers

    Homology

    Clone Names

    • 1110017O10Rik, F730029F15Rik

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in cognition ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    integral membrane protein GPR155
    Names
    GPR155 variant 3
    GPR155 variant 6

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001190297.2NP_001177226.1  integral membrane protein GPR155 isoform 1

      See identical proteins and their annotated locations for NP_001177226.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AL954713, AV115983, HM161763
      Consensus CDS
      CCDS50606.1
      UniProtKB/TrEMBL
      A2AWR3
      Related
      ENSMUSP00000075788.6, ENSMUST00000076463.12
      Conserved Domains (2) summary
      cd04443
      Location:749831
      DEP_GPR155; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in GPR155-like proteins. GRP155-like proteins, also known as PGR22, contain an N-terminal permease domain, a central transmembrane region and a C-terminal DEP domain. They are orphan receptors of the ...
      cl22894
      Location:36364
      Mem_trans; Membrane transport protein
    2. NM_001276443.1NP_001263372.1  integral membrane protein GPR155 isoform 3

      See identical proteins and their annotated locations for NP_001263372.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice site in the 3' coding region, which results in a frameshift, compared to variant 1. The encoded isoform (3) is shorter and has a distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AL954713, AV115983, HM161764
      UniProtKB/TrEMBL
      D7RXL9
      Conserved Domains (2) summary
      cl02442
      Location:749776
      DEP; DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is ...
      cl22894
      Location:36364
      Mem_trans; Membrane transport protein
    3. NM_001276444.1NP_001263373.1  integral membrane protein GPR155 isoform 4

      See identical proteins and their annotated locations for NP_001263373.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an in-frame exon in the coding region, compared to variant 1. The encoded isoform (4) is shorter, compared to isoform 1.
      Source sequence(s)
      AL954713, AV115983, HM161766
      Consensus CDS
      CCDS71075.1
      UniProtKB/TrEMBL
      A2AWR2
      Related
      ENSMUSP00000107675.2, ENSMUST00000112044.8
      Conserved Domains (2) summary
      cd04443
      Location:721803
      DEP_GPR155; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in GPR155-like proteins. GRP155-like proteins, also known as PGR22, contain an N-terminal permease domain, a central transmembrane region and a C-terminal DEP domain. They are orphan receptors of the ...
      cl22894
      Location:36364
      Mem_trans; Membrane transport protein

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      73171850..73216842 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500106.3XP_006500169.1  integral membrane protein GPR155 isoform X2

      See identical proteins and their annotated locations for XP_006500169.1

      UniProtKB/TrEMBL
      A2AWR3
      Conserved Domains (2) summary
      cd04443
      Location:749831
      DEP_GPR155; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in GPR155-like proteins. GRP155-like proteins, also known as PGR22, contain an N-terminal permease domain, a central transmembrane region and a C-terminal DEP domain. They are orphan receptors of the ...
      cl22894
      Location:36364
      Mem_trans; Membrane transport protein
    2. XM_006500104.3XP_006500167.1  integral membrane protein GPR155 isoform X1

      See identical proteins and their annotated locations for XP_006500167.1

      Conserved Domains (2) summary
      cd04443
      Location:762844
      DEP_GPR155; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in GPR155-like proteins. GRP155-like proteins, also known as PGR22, contain an N-terminal permease domain, a central transmembrane region and a C-terminal DEP domain. They are orphan receptors of the ...
      cl22894
      Location:49377
      Mem_trans; Membrane transport protein
    3. XM_006500105.3XP_006500168.1  integral membrane protein GPR155 isoform X1

      See identical proteins and their annotated locations for XP_006500168.1

      Conserved Domains (2) summary
      cd04443
      Location:762844
      DEP_GPR155; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in GPR155-like proteins. GRP155-like proteins, also known as PGR22, contain an N-terminal permease domain, a central transmembrane region and a C-terminal DEP domain. They are orphan receptors of the ...
      cl22894
      Location:49377
      Mem_trans; Membrane transport protein
    4. XM_006500107.4XP_006500170.1  integral membrane protein GPR155 isoform X3

      Related
      ENSMUST00000048504.10
      Conserved Domains (2) summary
      cl22894
      Location:49377
      Mem_trans; Membrane transport protein
      cl02442
      Location:762789
      DEP; DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is ...
    5. XM_006500108.5XP_006500171.1  integral membrane protein GPR155 isoform X4

      Conserved Domains (2) summary
      cl22894
      Location:49377
      Mem_trans; Membrane transport protein
      cl02442
      Location:762790
      DEP; DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is ...

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001080707.1: Suppressed sequence

      Description
      NM_001080707.1: This RefSeq was permanently suppressed because currently there is insufficient support for the transcript and the protein.
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