Ugt2a1 UDP glucuronosyltransferase 2 family, polypeptide A1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ugt2a1provided by MGI
Official Full Name: UDP glucuronosyltransferase 2 family, polypeptide A1provided by MGI
Primary source: MGI:MGI:2149905
See related: Ensembl:ENSMUSG00000106677 AllianceGenome:MGI:2149905
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Predicted to enable glucuronosyltransferase activity. Predicted to be involved in sensory perception of smell. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in nervous system; nose; and olfactory epithelium. Orthologous to several human genes including UGT2A2 (UDP glucuronosyltransferase family 2 member A2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Low expression observed in reference dataset See more
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Genomic context

Location:: 5 E1; 5 43.56 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	5	NC_000071.7 (87607349..87638730, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	5	NC_000071.6 (87459490..87490871, complement)

Chromosome 5 - NC_000071.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables UDP-glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables glucuronosyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables glucuronosyltransferase activity	ISA Inferred from Sequence Alignment more info	PubMed
enables glucuronosyltransferase activity	ISO Inferred from Sequence Orthology more info
enables glycosyltransferase activity	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in bile acid metabolic process	ISO Inferred from Sequence Orthology more info
involved_in cellular glucuronidation	IBA Inferred from Biological aspect of Ancestor more info
involved_in cellular glucuronidation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within lipid metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within response to stimulus	IEA Inferred from Electronic Annotation more info
involved_in sensory perception of chemical stimulus	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within sensory perception of smell	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: UDP-glucuronosyltransferase 2A1

Names: UDP glycosyltransferase 2 family, polypeptide A1; UDPGT 2A1; olfactory UDP glucuronosyltransferase

NP_444414.2

EC 2.4.1.17

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_053184.2 → NP_444414.2 UDP-glucuronosyltransferase 2A1 precursor

See identical proteins and their annotated locations for NP_444414.2

Status: VALIDATED

Source sequence(s)

AK140757, BC048926

Consensus CDS

CCDS39129.1

UniProtKB/Swiss-Prot

Q80X89, Q9ESE4

Related

ENSMUSP00000114583.2, ENSMUST00000147854.6

Conserved Domains (2) summary

PHA03392
Location:267 → 487

egt; ecdysteroid UDP-glucosyltransferase; Provisional

pfam00201
Location:21 → 516

UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase