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    Cfhr2 complement factor H-related 2 [ Mus musculus (house mouse) ]

    Gene ID: 545366, updated on 23-Jun-2021


    Official Symbol
    Cfhr2provided by MGI
    Official Full Name
    complement factor H-related 2provided by MGI
    Primary source
    See related
    Gene type
    protein coding
    RefSeq status
    Mus musculus
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    FHR-; FHR-B; Cfhrb_4/2
    Biased expression in liver adult (RPKM 84.9), liver E18 (RPKM 77.2) and 1 other tissue See more
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    Genomic context

    See Cfhr2 in Genome Data Viewer
    1; 1 F
    Exon count:
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (139738030..139786437, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (139810292..139858699, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (141706869..141755276, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 25619 Neighboring gene predicted gene, 41963 Neighboring gene predicted gene 16332 Neighboring gene RuvB-like protein 1 pseudogene Neighboring gene predicted gene, 26048

    Genomic regions, transcripts, and products


    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information


    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables complement component C3b binding IPI
    Inferred from Physical Interaction
    more info
    enables heparin binding IDA
    Inferred from Direct Assay
    more info
    Process Evidence Code Pubs
    involved_in regulation of complement activation ISO
    Inferred from Sequence Orthology
    more info
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    located_in extracellular space IDA
    Inferred from Direct Assay
    more info
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info

    General protein information

    Preferred Names
    complement factor H-related protein B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001025575.2NP_001020746.1  complement factor H-related protein B precursor

      See identical proteins and their annotated locations for NP_001020746.1

      Status: VALIDATED

      Source sequence(s)
      AC115748, AJ565908
      Consensus CDS
      ENSMUSP00000092065.4, ENSMUST00000094489.5
      Conserved Domains (1) summary
      CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J


    1. NC_000067.7 Reference GRCm39 C57BL/6J

      139738030..139786437 complement
      GenBank, FASTA, Sequence Viewer (Graphics)
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