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    Zfp37 zinc finger protein 37 [ Mus musculus (house mouse) ]

    Gene ID: 22696, updated on 23-Jun-2021

    Summary

    Official Symbol
    Zfp37provided by MGI
    Official Full Name
    zinc finger protein 37provided by MGI
    Primary source
    MGI:MGI:99181
    See related
    Ensembl:ENSMUSG00000028389
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Tz; Tzn; Zfp-3; Zfp-37
    Expression
    Biased expression in testis adult (RPKM 14.6), CNS E11.5 (RPKM 4.2) and 9 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Zfp37 in Genome Data Viewer
    Location:
    4 B3; 4 33.04 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (62107774..62127634, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (62189537..62209129, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (61850577..61869580, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene predicted gene 12909 Neighboring gene major urinary protein 21 Neighboring gene predicted gene, 30511 Neighboring gene predicted gene, 23148

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables zinc ion binding TAS
    Traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    zinc finger protein 37
    Names
    male germ cell-specific zinc finger protein
    zinc finger protein 37 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290350.1NP_001277279.1  zinc finger protein 37 isoform 1

      See identical proteins and their annotated locations for NP_001277279.1

      Status: VALIDATED

      Source sequence(s)
      AL683829, BC024863, BC063757, BM228461, CJ078183, CO434318
      Consensus CDS
      CCDS71400.1
      UniProtKB/Swiss-Prot
      P17141
      UniProtKB/TrEMBL
      Q6P3Z4, Q8R1B1
      Related
      ENSMUSP00000070463.4, ENSMUST00000068822.4
      Conserved Domains (6) summary
      cd07765
      Location:1542
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
      smart00349
      Location:1562
      KRAB; krueppel associated box
      COG5048
      Location:124486
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:397417
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:451473
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:353378
      zf-H2C2_2; Zinc-finger double domain
    2. NM_001290351.1NP_001277280.1  zinc finger protein 37 isoform 3

      Status: VALIDATED

      Source sequence(s)
      BC024863, BM228461, CJ078183, CO434318
      Consensus CDS
      CCDS89756.1
      UniProtKB/TrEMBL
      A0A1Y7VLM5, Q8R1B1
      Related
      ENSMUSP00000152266.2, ENSMUST00000221329.2
      Conserved Domains (6) summary
      cd07765
      Location:139
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
      smart00349
      Location:1259
      KRAB; krueppel associated box
      COG5048
      Location:121483
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:394414
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:448470
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:350375
      zf-H2C2_2; Zinc-finger double domain
    3. NM_001290353.1NP_001277282.1  zinc finger protein 37 isoform 4

      See identical proteins and their annotated locations for NP_001277282.1

      Status: VALIDATED

      Source sequence(s)
      BC024863, BC063757, BM228461, CF915126
      Consensus CDS
      CCDS89754.1
      UniProtKB/TrEMBL
      A0A1Y7VJF3, Q6P3Z4, Q8R1B1
      Related
      ENSMUSP00000152400.2, ENSMUST00000222748.2
      Conserved Domains (3) summary
      COG5048
      Location:83445
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:356376
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:509533
      zf-H2C2_2; Zinc-finger double domain
    4. NM_001348347.1NP_001335276.1  zinc finger protein 37 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL683829
      Consensus CDS
      CCDS89754.1
      UniProtKB/TrEMBL
      A0A1Y7VJF3
      Conserved Domains (3) summary
      COG5048
      Location:83445
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:356376
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:509533
      zf-H2C2_2; Zinc-finger double domain
    5. NM_009554.4NP_033580.3  zinc finger protein 37 isoform 2

      See identical proteins and their annotated locations for NP_033580.3

      Status: VALIDATED

      Source sequence(s)
      BC024863, BC063757, BM228461, CJ078183
      Consensus CDS
      CCDS89755.1
      UniProtKB/TrEMBL
      Q6P3Z4, Q8R1B1
      Related
      ENSMUSP00000152491.2, ENSMUST00000222050.2
      Conserved Domains (6) summary
      cd07765
      Location:138
      KRAB_A-box; KRAB (Kruppel-associated box) domain -A box
      smart00349
      Location:958
      KRAB; krueppel associated box
      COG5048
      Location:120482
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:393413
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:447469
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:349374
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      62107774..62127634 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006537800.4XP_006537863.1  zinc finger protein 37 isoform X1

      Conserved Domains (5) summary
      smart00349
      Location:1361
      KRAB; krueppel associated box
      COG5048
      Location:123485
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:396416
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:506528
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:549573
      zf-H2C2_2; Zinc-finger double domain
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