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    Ugp2 UDP-glucose pyrophosphorylase 2 [ Mus musculus (house mouse) ]

    Gene ID: 216558, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ugp2provided by MGI
    Official Full Name
    UDP-glucose pyrophosphorylase 2provided by MGI
    Primary source
    MGI:MGI:2183447
    See related
    Ensembl:ENSMUSG00000001891
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    UDPGP; UGPase
    Expression
    Broad expression in placenta adult (RPKM 25.7), bladder adult (RPKM 25.1) and 21 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ugp2 in Genome Data Viewer
    Location:
    11 A3.1; 11 13.89 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (21271126..21321267, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (21321126..21371267, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 11 NC_000077.5 (21221141..21270882, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene VPS54 GARP complex subunit Neighboring gene predicted gene, 23582 Neighboring gene tudor and KH domain containing protein pseudogene Neighboring gene microRNA 1933 Neighboring gene heterogeneous nuclear ribonucleoprotein R pseudogene Neighboring gene RAB5C, member RAS oncogene family pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC38262

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables UTP:glucose-1-phosphate uridylyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables UTP:glucose-1-phosphate uridylyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables glucose binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables pyrimidine ribonucleotide binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables uridylyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in UDP-glucose metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in UDP-glucose metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in brain development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in glucose 1-phosphate metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in glycogen biosynthetic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in glycogen metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    UTP--glucose-1-phosphate uridylyltransferase
    Names
    uridindiphosphoglucosepyrophosphorylase 2
    NP_001277563.1
    NP_647458.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001290634.1NP_001277563.1  UTP--glucose-1-phosphate uridylyltransferase isoform 2

      See identical proteins and their annotated locations for NP_001277563.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate 5'-terminal exon, differs in its 5' UTR, and uses a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AK033445, AL833772, BQ033764, BY273488, CJ098156
      Consensus CDS
      CCDS70148.1
      UniProtKB/Swiss-Prot
      Q91ZJ5
      UniProtKB/TrEMBL
      Q3U548
      Related
      ENSMUSP00000056324.6, ENSMUST00000060895.6
      Conserved Domains (1) summary
      pfam01704
      Location:46462
      UDPGP; UTP--glucose-1-phosphate uridylyltransferase
    2. NM_139297.6NP_647458.1  UTP--glucose-1-phosphate uridylyltransferase isoform 1

      See identical proteins and their annotated locations for NP_647458.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK033445, AL833772, BQ033764, BY729023
      Consensus CDS
      CCDS24464.1
      UniProtKB/Swiss-Prot
      Q91ZJ5
      Related
      ENSMUSP00000099939.5, ENSMUST00000102875.11
      Conserved Domains (1) summary
      pfam01704
      Location:57473
      UDPGP; UTP--glucose-1-phosphate uridylyltransferase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      21271126..21321267 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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