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    Slco1a5 solute carrier organic anion transporter family, member 1a5 [ Mus musculus (house mouse) ]

    Gene ID: 108096, updated on 23-Jun-2021

    Summary

    Official Symbol
    Slco1a5provided by MGI
    Official Full Name
    solute carrier organic anion transporter family, member 1a5provided by MGI
    Primary source
    MGI:MGI:1351865
    See related
    Ensembl:ENSMUSG00000063975
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Oa; Slc2; Oatp3; Oatp-3; Slc21a7
    Expression
    Biased expression in genital fat pad adult (RPKM 1.3), liver adult (RPKM 0.4) and 9 other tissues See more
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    Genomic context

    See Slco1a5 in Genome Data Viewer
    Location:
    6; 6 G2
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (142179953..142268707, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (142234227..142322981, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (142182750..142271470, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene predicted gene 6614 Neighboring gene solute carrier organic anion transporter family, member 1a6 Neighboring gene predicted gene, 18159 Neighboring gene uncharacterized LOC118567420 Neighboring gene 60S ribosomal protein L18 pseudogene Neighboring gene islet amyloid polypeptide Neighboring gene pyridine nucleotide-disulphide oxidoreductase domain 1 Neighboring gene RecQ protein-like Neighboring gene golgi transport 1B

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in bile acid and bile salt transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in bile acid and bile salt transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in intestinal absorption ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in monocarboxylic acid transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in organic anion transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sodium-independent organic anion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in brush border membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    solute carrier organic anion transporter family member 1A5
    Names
    organic anion-transporting polypeptide 3
    sodium-independent organic anion transporter 3
    solute carrier family 21 (organic anion transporter), member 7
    solute carrier family 21 member 7

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001267707.1NP_001254636.1  solute carrier organic anion transporter family member 1A5

      See identical proteins and their annotated locations for NP_001254636.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC102125, FQ790388
      Consensus CDS
      CCDS57464.1
      UniProtKB/Swiss-Prot
      Q91YY5
      UniProtKB/TrEMBL
      A0A0G2JDD1
      Related
      ENSMUSP00000137607.2, ENSMUST00000111825.10
      Conserved Domains (3) summary
      cd06174
      Location:23397
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      cd01330
      Location:436488
      KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
      TIGR00805
      Location:1625
      oat; sodium-independent organic anion transporter
    2. NM_130861.3NP_570931.1  solute carrier organic anion transporter family member 1A5

      See identical proteins and their annotated locations for NP_570931.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK029706
      Consensus CDS
      CCDS57464.1
      UniProtKB/Swiss-Prot
      Q91YY5
      UniProtKB/TrEMBL
      A0A0G2JDD1
      Related
      ENSMUSP00000080116.4, ENSMUST00000081380.10
      Conserved Domains (3) summary
      cd06174
      Location:23397
      MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
      cd01330
      Location:436488
      KAZAL_SLC21; The kazal-type serine protease inhibitor domain has been detected in an extracellular loop region of solute carrier 21 (SLC21) family members (organic anion transporters) , which may regulate the specificity of anion uptake. The KAZAL_SLC21 domain is a ...
      TIGR00805
      Location:1625
      oat; sodium-independent organic anion transporter

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      142179953..142268707 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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