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    Plpp6 phospholipid phosphatase 6 [ Mus musculus (house mouse) ]

    Gene ID: 74411, updated on 23-Jun-2021

    Summary

    Official Symbol
    Plpp6provided by MGI
    Official Full Name
    phospholipid phosphatase 6provided by MGI
    Primary source
    MGI:MGI:1921661
    See related
    Ensembl:ENSMUSG00000040105
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ppa; Ppapdc2; 4932443D16Rik
    Orthologs
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    Genomic context

    See Plpp6 in Genome Data Viewer
    Location:
    19; 19 C1
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (28941320..28944201)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (28963920..28966801)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (29038410..29041291)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 52404 Neighboring gene solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1 Neighboring gene eukaryotic translation elongation factor 1 alpha 1 pseudogene Neighboring gene spermatogenesis associated 6 like Neighboring gene phytanoyl-CoA hydroxylase pseudogene Neighboring gene tektin 5 pseudogene

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables lipid phosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables sphingosine-1-phosphate phosphatase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in phospholipid dephosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in phospholipid dephosphorylation ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    phospholipid phosphatase 6
    Names
    phosphatidic acid phosphatase type 2 domain containing 2
    phosphatidic acid phosphatase type 2 domain-containing protein 2
    presqualene diphosphate phosphatase
    NP_083198.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028922.3NP_083198.1  phospholipid phosphatase 6

      See identical proteins and their annotated locations for NP_083198.1

      Status: VALIDATED

      Source sequence(s)
      AK016572, AK149181, BC052412
      Consensus CDS
      CCDS29728.1
      UniProtKB/Swiss-Prot
      Q9D4F2
      Related
      ENSMUSP00000047776.3, ENSMUST00000045674.4
      Conserved Domains (2) summary
      COG0671
      Location:204266
      PgpB; Membrane-associated phospholipid phosphatase [Lipid transport and metabolism]
      cd03391
      Location:115273
      PAP2_containing_2_like; PAP2, subfamily similar to human phosphatidic_acid_phosphatase_type_2_domain_containing_2. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to eukaryota, lacks functional characterization and may act as a ...

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      28941320..28944201
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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