Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ZEB1 zinc finger E-box binding homeobox 1 [ Homo sapiens (human) ]

    Gene ID: 6935, updated on 6-Sep-2021

    Summary

    Official Symbol
    ZEB1provided by HGNC
    Official Full Name
    zinc finger E-box binding homeobox 1provided by HGNC
    Primary source
    HGNC:HGNC:11642
    See related
    Ensembl:ENSG00000148516 MIM:189909
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    BZP; TCF8; AREB6; FECD6; NIL2A; PPCD3; ZFHEP; ZFHX1A; DELTAEF1
    Summary
    This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2010]
    Expression
    Ubiquitous expression in endometrium (RPKM 12.8), brain (RPKM 12.1) and 23 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See ZEB1 in Genome Data Viewer
    Location:
    10p11.22
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) 10 NC_000010.11 (31318417..31529804)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (31607346..31818732)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376481 Neighboring gene uncharacterized LOC105376483 Neighboring gene long intergenic non-protein coding RNA 2664 Neighboring gene RNA, 5S ribosomal pseudogene 309 Neighboring gene ZEB1 antisense RNA 1 Neighboring gene putative UPF0607 protein FLJ37424 Neighboring gene serine palmitoyltransferase long chain base subunit 1 pseudogene 1 Neighboring gene Sharpr-MPRA regulatory region 3516 Neighboring gene uncharacterized LOC105376484 Neighboring gene glutamate dehydrogenase 1 pseudogene 5 Neighboring gene macrophage enriched lincRNA repressor of IFN-gamma signaling

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    Corneal dystrophy, Fuchs endothelial, 6
    MedGen: C2750448 OMIM: 613270 GeneReviews: Not available
    Compare labs
    Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution.
    GeneReviews: Not available
    Posterior polymorphous corneal dystrophy 3
    MedGen: C1836724 OMIM: 609141 GeneReviews: Not available
    Compare labs

    HIV-1 interactions

    Protein interactions

    Protein Gene Interaction Pubs
    Nef nef HIV-1 Nef upregulates the expression of transcription factor 8 in HeLa cells PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC133261

    Gene Ontology Provided by GOA

    Component Evidence Code Pubs
    located_in chromatin ISA
    Inferred from Sequence Alignment
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
     
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    zinc finger E-box-binding homeobox 1
    Names
    delta-crystallin enhancer binding factor 1
    negative regulator of IL2
    posterior polymorphous corneal dystrophy 3
    transcription factor 8 (represses interleukin 2 expression)
    zinc finger homeodomain enhancer-binding protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_017048.1 RefSeqGene

      Range
      5045..215632
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001128128.3NP_001121600.1  zinc finger E-box-binding homeobox 1 isoform a

      See identical proteins and their annotated locations for NP_001121600.1

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Consensus CDS
      CCDS44370.1
      UniProtKB/Swiss-Prot
      P37275
      UniProtKB/TrEMBL
      B2RBI8
      Related
      ENSP00000391612.2, ENST00000446923.7
      Conserved Domains (5) summary
      smart00389
      Location:577613
      HOX; Homeodomain
      COG5271
      Location:1181
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00017
      Location:890910
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:224246
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:930955
      zf-H2C2_2; Zinc-finger double domain
    2. NM_001174093.2NP_001167564.1  zinc finger E-box-binding homeobox 1 isoform c

      Status: REVIEWED

      Source sequence(s)
      AI086650, AL831979, BC112392, BQ003893, BX111519, DC299346
      Consensus CDS
      CCDS53506.1
      UniProtKB/Swiss-Prot
      P37275
      Related
      ENSP00000452787.1, ENST00000560721.6
      Conserved Domains (5) summary
      smart00389
      Location:573609
      HOX; Homeodomain
      COG5048
      Location:909962
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:886906
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:220242
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:926951
      zf-H2C2_2; Zinc-finger double domain
    3. NM_001174094.2NP_001167565.1  zinc finger E-box-binding homeobox 1 isoform d

      Status: REVIEWED

      Source sequence(s)
      AI086650, AK311116, AK311187, AK311557, AK314683, AL831979, BQ003893, BX111519, U12170
      UniProtKB/Swiss-Prot
      P37275
      UniProtKB/TrEMBL
      B2RBI8
      Conserved Domains (5) summary
      smart00389
      Location:576612
      HOX; Homeodomain
      COG5271
      Location:1180
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00017
      Location:889909
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:223245
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:929954
      zf-H2C2_2; Zinc-finger double domain
    4. NM_001174095.2NP_001167566.1  zinc finger E-box-binding homeobox 1 isoform e

      Status: REVIEWED

      Source sequence(s)
      AI086650, AK300830, AK314683, AL831979, BQ003893, BX111519, DC299346, U12170
      Consensus CDS
      CCDS53507.1
      UniProtKB/Swiss-Prot
      P37275
      UniProtKB/TrEMBL
      B2RBI8
      Related
      ENSP00000444891.2, ENST00000542815.7
      Conserved Domains (5) summary
      smart00389
      Location:526562
      HOX; Homeodomain
      COG5048
      Location:862915
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:839859
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:173195
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:879904
      zf-H2C2_2; Zinc-finger double domain
    5. NM_001174096.2NP_001167567.1  zinc finger E-box-binding homeobox 1 isoform f

      See identical proteins and their annotated locations for NP_001167567.1

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Consensus CDS
      CCDS53505.1
      UniProtKB/Swiss-Prot
      P37275
      Related
      ENSP00000415961.2, ENST00000424869.6
      Conserved Domains (4) summary
      smart00389
      Location:594630
      HOX; Homeodomain
      sd00017
      Location:907927
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:241263
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:947972
      zf-H2C2_2; Zinc-finger double domain
    6. NM_001323638.2NP_001310567.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL161935, AL355148, BX647794
      Related
      ENST00000488625.6
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    7. NM_001323641.2NP_001310570.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AK294775, AL161935
      UniProtKB/TrEMBL
      B4DGU2
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    8. NM_001323642.2NP_001310571.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    9. NM_001323643.2NP_001310572.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    10. NM_001323644.2NP_001310573.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    11. NM_001323645.2NP_001310574.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    12. NM_001323646.2NP_001310575.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AK311372, AL117340, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    13. NM_001323647.2NP_001310576.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    14. NM_001323648.2NP_001310577.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    15. NM_001323649.2NP_001310578.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    16. NM_001323650.2NP_001310579.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    17. NM_001323651.2NP_001310580.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AK307510, AL158080, AL161935
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    18. NM_001323652.2NP_001310581.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL161935, AL355148, DB276952
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    19. NM_001323653.2NP_001310582.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL161935, AL355148, AL831979
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    20. NM_001323654.2NP_001310583.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AK308822, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    21. NM_001323655.2NP_001310584.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL161935, AL355148, BX954549
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    22. NM_001323656.2NP_001310585.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    23. NM_001323657.2NP_001310586.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    24. NM_001323658.2NP_001310587.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL161935, AL355148, DC403144
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    25. NM_001323659.2NP_001310588.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    26. NM_001323660.2NP_001310589.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    27. NM_001323661.2NP_001310590.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AK309399, AL158080, AL161935, AL355148, DC375708
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    28. NM_001323662.2NP_001310591.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    29. NM_001323663.2NP_001310592.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    30. NM_001323664.2NP_001310593.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    31. NM_001323665.2NP_001310594.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    32. NM_001323666.2NP_001310595.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    33. NM_001323671.2NP_001310600.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    34. NM_001323672.2NP_001310601.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    35. NM_001323673.2NP_001310602.1  zinc finger E-box-binding homeobox 1 isoform g

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    36. NM_001323674.2NP_001310603.1  zinc finger E-box-binding homeobox 1 isoform h

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
    37. NM_001323675.2NP_001310604.1  zinc finger E-box-binding homeobox 1 isoform i

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
    38. NM_001323676.2NP_001310605.1  zinc finger E-box-binding homeobox 1 isoform j

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
    39. NM_001323677.2NP_001310606.1  zinc finger E-box-binding homeobox 1 isoform k

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
    40. NM_001323678.2NP_001310607.1  zinc finger E-box-binding homeobox 1 isoform l

      Status: REVIEWED

      Source sequence(s)
      AL117340, AL158080, AL161935, AL355148
    41. NM_030751.6NP_110378.3  zinc finger E-box-binding homeobox 1 isoform b

      See identical proteins and their annotated locations for NP_110378.3

      Status: REVIEWED

      Source sequence(s)
      AI086650, AK314683, AL831979, BQ003893, BX111519, U12170
      Consensus CDS
      CCDS7169.1
      UniProtKB/Swiss-Prot
      P37275
      UniProtKB/TrEMBL
      B2RBI8
      Related
      ENSP00000319248.9, ENST00000320985.14
      Conserved Domains (5) summary
      smart00389
      Location:593629
      HOX; Homeodomain
      COG5271
      Location:27197
      MDN1; Midasin, AAA ATPase with vWA domain, involved in ribosome maturation [Translation, ribosomal structure and biogenesis]
      sd00017
      Location:906926
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:240262
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:946971
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p13 Primary Assembly

      Range
      31318417..31529804
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006717498.2XP_006717561.1  zinc finger E-box-binding homeobox 1 isoform X1

      See identical proteins and their annotated locations for XP_006717561.1

      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    2. XM_017016597.1XP_016872086.1  zinc finger E-box-binding homeobox 1 isoform X1

      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    3. XM_011519643.2XP_011517945.1  zinc finger E-box-binding homeobox 1 isoform X1

      See identical proteins and their annotated locations for XP_011517945.1

      Conserved Domains (4) summary
      smart00389
      Location:375411
      HOX; Homeodomain
      sd00017
      Location:688708
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:2244
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728753
      zf-H2C2_2; Zinc-finger double domain
    Support Center