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    Rasd2 RASD family, member 2 [ Mus musculus (house mouse) ]

    Gene ID: 75141, updated on 5-Jan-2022

    Summary

    Official Symbol
    Rasd2provided by MGI
    Official Full Name
    RASD family, member 2provided by MGI
    Primary source
    MGI:MGI:1922391
    See related
    Ensembl:ENSMUSG00000034472
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rhes; TEM2; TEM-2; AU045414; 4930526B11Rik
    Summary
    Predicted to enable several functions, including G-protein beta-subunit binding activity; GTP binding activity; and ubiquitin conjugating enzyme binding activity. Involved in dopaminergic synaptic transmission and locomotory behavior. Predicted to be located in plasma membrane. Orthologous to human RASD2 (RASD family member 2). [provided by Alliance of Genome Resources, Nov 2021]
    Expression
    Broad expression in cortex adult (RPKM 15.5), frontal lobe adult (RPKM 12.6) and 18 other tissues See more
    Orthologs
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    Genomic context

    See Rasd2 in Genome Data Viewer
    Location:
    8; 8 C1
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (75940572..75950741)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (75213944..75224113)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (77737843..77748012)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene heme oxygenase 1 Neighboring gene minichromosome maintenance complex component 5 Neighboring gene predicted gene 9644 Neighboring gene uridine monophosphate kinase, pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G-protein beta-subunit binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTP binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol 3-kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin conjugating enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    GTP-binding protein Rhes
    Names
    ras homolog enriched in striatum
    NP_083458.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029182.1NP_083458.1  GTP-binding protein Rhes

      See identical proteins and their annotated locations for NP_083458.1

      Status: VALIDATED

      Source sequence(s)
      AC076974
      Consensus CDS
      CCDS52602.1
      UniProtKB/Swiss-Prot
      P63032
      Related
      ENSMUSP00000118070.2, ENSMUST00000139848.8
      Conserved Domains (1) summary
      cd04143
      Location:20266
      Rhes_like; Ras homolog enriched in striatum (Rhes) and activator of G-protein signaling 1 (Dexras1/AGS1)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      75940572..75950741
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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