FBP1 fructose-bisphosphatase 1 [Canis lupus familiaris (dog)] - Gene

Summary

Official Symbol: FBP1provided by VGNC
Official Full Name: fructose-bisphosphatase 1provided by VGNC
Primary source: VGNC:VGNC:40757
See related: Ensembl:ENSCAFG00845005020
Gene type: protein coding
RefSeq status: MODEL
Organism: Canis lupus familiaris (sub-species: familiaris)
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae; Canis
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 1

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	ROS_Cfam_1.0 (GCF_014441545.1)	1	NC_051805.1 (72404539..72429921)
106	current	Dog10K_Boxer_Tasha (GCF_000002285.5)	1	NC_006583.4 (72861998..72887376)
106	current	UU_Cfam_GSD_1.0 (GCF_011100685.1)	1	NC_049222.1 (72686298..72711910)
106	current	UMICH_Zoey_3.1 (GCF_005444595.1)	1	NC_049261.1 (72215481..72240826)
106	current	UNSW_CanFamBas_1.0 (GCF_013276365.1)	1	NC_049742.1 (71981002..72006401)

Chromosome 1 - NC_051805.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables fructose 1,6-bisphosphate 1-phosphatase activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in fructose 1,6-bisphosphate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in fructose 6-phosphate metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in fructose metabolic process	IEA Inferred from Electronic Annotation more info	PubMed
involved_in gluconeogenesis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in sucrose biosynthetic process	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info	PubMed
located_in cytosol	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: fructose-1,6-bisphosphatase 1

XP_005615849.1

EC 3.1.3.11

XP_038322130.1

EC 3.1.3.11

XP_038322131.1

EC 3.1.3.11

XP_038382828.1

EC 3.1.3.11

XP_038382829.1

EC 3.1.3.11

XP_038447129.1

EC 3.1.3.11

XP_038447130.1

EC 3.1.3.11

XP_038510926.1

EC 3.1.3.11

XP_038510927.1

EC 3.1.3.11

XP_848306.1

EC 3.1.3.11

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Canis lupus familiaris Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ROS_Cfam_1.0

Genomic

NC_051805.1 Reference ROS_Cfam_1.0

Range

72404539..72429921

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038654998.1 → XP_038510926.1 fructose-1,6-bisphosphatase 1 isoform X1

UniProtKB/TrEMBL

A0A8C0MEJ0, A0A8C0QC07, A0A8C0R6H2, A0A8I3MZ42

Related

ENSCAFP00845007099.1, ENSCAFT00845009004.1

Conserved Domains (1) summary

cd00354
Location:18 → 332

FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...
XM_038654999.1 → XP_038510927.1 fructose-1,6-bisphosphatase 1 isoform X2

UniProtKB/TrEMBL

A0A8C0MRD0, A0A8I3MWI1

Related

ENSCAFP00845007104.1, ENSCAFT00845009009.1

Conserved Domains (1) summary

cd00354
Location:1 → 279

FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...

Alternate UMICH_Zoey_3.1

Genomic

NC_049261.1 Alternate UMICH_Zoey_3.1

Range

72215481..72240826

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038466202.1 → XP_038322130.1 fructose-1,6-bisphosphatase 1 isoform X1

Conserved Domains (1) summary

cd00354
Location:18 → 332

FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...
XM_038466203.1 → XP_038322131.1 fructose-1,6-bisphosphatase 1 isoform X2

Conserved Domains (1) summary

cd00354
Location:1 → 279

FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...

Alternate UNSW_CanFamBas_1.0

Genomic

NC_049742.1 Alternate UNSW_CanFamBas_1.0

Range

71981002..72006401

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038591201.1 → XP_038447129.1 fructose-1,6-bisphosphatase 1 isoform X1
XM_038591202.1 → XP_038447130.1 fructose-1,6-bisphosphatase 1 isoform X2

Alternate UU_Cfam_GSD_1.0

Genomic

NC_049222.1 Alternate UU_Cfam_GSD_1.0

Range

72686298..72711910

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_038526900.1 → XP_038382828.1 fructose-1,6-bisphosphatase 1 isoform X1

UniProtKB/TrEMBL

A0A8C0MEJ0, A0A8C0QC07, A0A8C0R6H2, A0A8I3MZ42

Conserved Domains (1) summary

cd00354
Location:18 → 332

FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...
XM_038526901.1 → XP_038382829.1 fructose-1,6-bisphosphatase 1 isoform X2

UniProtKB/TrEMBL

A0A8C0MRD0, A0A8I3MWI1

Conserved Domains (1) summary

cd00354
Location:1 → 279

FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...

Alternate Dog10K_Boxer_Tasha Primary Assembly

Genomic

NC_006583.4 Alternate Dog10K_Boxer_Tasha Primary Assembly

Range

72861998..72887376

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_843213.3 → XP_848306.1 fructose-1,6-bisphosphatase 1 isoform X1

UniProtKB/TrEMBL

A0A8C0MEJ0, A0A8C0QC07, A0A8C0R6H2, A0A8I3MZ42

Conserved Domains (1) summary

cd00354
Location:18 → 332

FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...
XM_005615792.3 → XP_005615849.1 fructose-1,6-bisphosphatase 1 isoform X2

UniProtKB/TrEMBL

A0A8C0MRD0, A0A8I3MWI1

Conserved Domains (1) summary

cd00354
Location:1 → 279

FBPase; Fructose-1,6-bisphosphatase, an enzyme that catalyzes the hydrolysis of fructose-1,6-biphosphate into fructose-6-phosphate and is critical in gluconeogenesis pathway. The alignment model also includes chloroplastic FBPases and sedoheptulose-1, ...