BMAL2 basic helix-loop-helix ARNT like 2 [Homo sapiens (human)] - Gene

Summary

Official Symbol: BMAL2provided by HGNC
Official Full Name: basic helix-loop-helix ARNT like 2provided by HGNC
Primary source: HGNC:HGNC:18984
See related: Ensembl:ENSG00000029153 MIM:614517; AllianceGenome:HGNC:18984
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: CLIF; MOP9; PASD9; ARNTL2; bHLHe6
Summary: This gene encodes a basic helix-loop-helix transcription factor belonging to the PAS (PER, ARNT, SIM) superfamily. The PAS proteins play important roles in adaptation to low atmospheric and cellular oxygen levels, exposure to certain environmental pollutants, and diurnal oscillations in light and temperature. This protein forms a transcriptionally active heterodimer with the circadian CLOCK protein, the structurally related MOP4, and hypoxia-inducible factors, such as HIF1alpha. Consistent with its role as a biologically relevant partner of circadian and hypoxia factors, this protein is coexpressed in regions of the brain such as the thalamus, hypothalamus, and amygdala. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
Expression: Broad expression in esophagus (RPKM 6.4), appendix (RPKM 3.2) and 17 other tissues See more
Orthologs: mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 12p11.23

Exon count:: 19

Annotation release	Status	Assembly	Chr	Location
RS_2023_10	current	GRCh38.p14 (GCF_000001405.40)	12	NC_000012.12 (27332836..27425286)
RS_2023_10	current	T2T-CHM13v2.0 (GCF_009914755.1)	12	NC_060936.1 (27204471..27296954)
105.20220307	previous assembly	GRCh37.p13 (GCF_000001405.25)	12	NC_000012.11 (27485769..27578219)

Chromosome 12 - NC_000012.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: HPA RNA-seq normal tissues
Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
BioProject: PRJEB4337
Publication: PMID 24309898
Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

ARNTL2 promotes pancreatic ductal adenocarcinoma progression through TGF/BETA pathway and is regulated by miR-26a-5p.
Title: ARNTL2 promotes pancreatic ductal adenocarcinoma progression through TGF/BETA pathway and is regulated by miR-26a-5p.
Data indicate that high transcription factor ARNTL2 is a top predictor of lung adenocarcinoma patient outcome.
Title: An Arntl2-Driven Secretome Enables Lung Adenocarcinoma Metastatic Self-Sufficiency.
BMAL2 rs7958822 genotype is associated with type 2 diabetes in obese men and women; an interaction between BMAL2 rs7958822 genotype and obesity was observed in men
Title: Association between brain-muscle-ARNT-like protein-2 (BMAL2) gene polymorphism and type 2 diabetes mellitus in obese Japanese individuals: A cross-sectional analysis of the Japan Multi-institutional Collaborative Cohort Study.
The prevalence of C carriers in BMAL2 gene rs2306074 T/C in Alzheimer disease patients was significantly higher than that of control subjects
Title: The polymorphism of ARNTL2 (BMAL2) gene rs2306074 C>T is associated with susceptibility of Alzheimer disease in Chinese population.
there is significant association between diurnal preference and a polymorphism in PER3 and a novel nominally significant association between diurnal preference and a polymorphism in ARNTL2
Title: Polymorphisms in the circadian expressed genes PER3 and ARNTL2 are associated with diurnal preference and GNβ3 with sleep measures.
ARNTL2 expression is increased in colorectal cancer and in a highly proliferative colon cancer cell line and is related to tumor invasiveness and aggressiveness.
Title: ARNTL2 and SERPINE1: potential biomarkers for tumor aggressiveness in colorectal cancer.
results show a difference in the expression pattern of Bmal2, but not Clock and Dec1 in PD.
Title: Decreased expression of Bmal2 in patients with Parkinson's disease.
Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.
PER2 is inhibited by BMAL2-CLOCK, which reemphasizes its negative role and a positive role of BMAL2 in circadian transcription
Title: Preferential inhibition of BMAL2-CLOCK activity by PER2 reemphasizes its negative role and a positive role of BMAL2 in the circadian transcription.
Observational study of gene-disease association. (HuGE Navigator)
Title: Circadian clock gene polymorphisms in alcohol use disorders and alcohol consumption.

Submit: New GeneRIF Correction See all GeneRIFs (13)

Phenotypes

Go to the top of the page Help

Find tests for this gene in the NIH Genetic Testing Registry (GTR)

Review eQTL and phenotype association data in this region using PheGenI

Variation

Go to the top of the page Help

See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

D11S2921 (e-PCR)
- UniSTS:152074

ha2836 (e-PCR)
- UniSTS:515599

G62346 (e-PCR)
- UniSTS:139381

D1S1425 (e-PCR)
- UniSTS:149621

D11S3114 (e-PCR)
- UniSTS:152207

G62259 (e-PCR)
- UniSTS:139417

RH99013 (e-PCR)
- UniSTS:87498

Gene Ontology Provided by GOA

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity	NAS Non-traceable Author Statement more info	PubMed
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IDA Inferred from Direct Assay more info	PubMed
enables DNA-binding transcription factor activity, RNA polymerase II-specific	ISA Inferred from Sequence Alignment more info
enables E-box binding	IDA Inferred from Direct Assay more info	PubMed
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IDA Inferred from Direct Assay more info	PubMed
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in circadian regulation of gene expression	IDA Inferred from Direct Assay more info	PubMed
acts_upstream_of_or_within circadian rhythm	IDA Inferred from Direct Assay more info	PubMed
involved_in entrainment of circadian clock	NAS Non-traceable Author Statement more info	PubMed
involved_in positive regulation of DNA-templated transcription	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of circadian rhythm	IDA Inferred from Direct Assay more info	PubMed
involved_in positive regulation of circadian rhythm	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of DNA-templated transcription	NAS Non-traceable Author Statement more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of transcription by RNA polymerase II	IDA Inferred from Direct Assay more info	PubMed

Component	Evidence Code	Pubs
part_of CLOCK-BMAL transcription complex	IPI Inferred from Physical Interaction more info	PubMed
part_of aryl hydrocarbon receptor complex	IBA Inferred from Biological aspect of Ancestor more info
part_of chromatin	ISA Inferred from Sequence Alignment more info
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleolus	IDA Inferred from Direct Assay more info
located_in nucleoplasm	IDA Inferred from Direct Assay more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	NAS Non-traceable Author Statement more info	PubMed

General protein information

Go to the top of the page Help

Preferred Names: basic helix-loop-helix ARNT-like protein 2

Names: CYCLE-like factor; PAS domain-containing protein 9; aryl hydrocarbon receptor nuclear translocator like 2; basic-helix-loop-helix-PAS protein MOP9; brain and muscle ARNT-like 2; class E basic helix-loop-helix protein 6; member of PAS protein 9; member of PAS superfamily 9; transcription factor BMAL2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

NG_030359.2 RefSeqGene

Range

4983..97433

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001248002.3 → NP_001234931.1 basic helix-loop-helix ARNT-like protein 2 isoform 2

See identical proteins and their annotated locations for NP_001234931.1

Status: REVIEWED

Source sequence(s)

AC068794, AC092829

Consensus CDS

CCDS58219.1

UniProtKB/TrEMBL

H0Y5R1

Related

ENSP00000312247.5, ENST00000311001.9

Conserved Domains (4) summary

cd00130
Location:356 → 454

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

pfam00010
Location:95 → 147

HLH; Helix-loop-helix DNA-binding domain

pfam00989
Location:167 → 273

PAS; PAS fold

pfam14598
Location:356 → 458

PAS_11; PAS domain
NM_001248003.3 → NP_001234932.1 basic helix-loop-helix ARNT-like protein 2 isoform 3

See identical proteins and their annotated locations for NP_001234932.1

Status: REVIEWED

Source sequence(s)

AC068794, AC092829

Consensus CDS

CCDS58221.1

UniProtKB/TrEMBL

H0Y5R1

Related

ENSP00000379238.2, ENST00000395901.6

Conserved Domains (3) summary

cd00130
Location:155 → 250

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

pfam00010
Location:73 → 124

HLH; Helix-loop-helix DNA-binding domain

cl25986
Location:333 → 435

PAS_3; PAS fold
NM_001248004.3 → NP_001234933.1 basic helix-loop-helix ARNT-like protein 2 isoform 4

See identical proteins and their annotated locations for NP_001234933.1

Status: REVIEWED

Source sequence(s)

AC068794, AC092829

Consensus CDS

CCDS58220.1

UniProtKB/TrEMBL

H0Y5R1

Related

ENSP00000261178.5, ENST00000261178.9

Conserved Domains (3) summary

cd00130
Location:144 → 239

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

pfam00010
Location:62 → 113

HLH; Helix-loop-helix DNA-binding domain

cl25986
Location:322 → 424

PAS_3; PAS fold
NM_001248005.3 → NP_001234934.1 basic helix-loop-helix ARNT-like protein 2 isoform 5

Status: REVIEWED

Source sequence(s)

AC068794, AC092829

Consensus CDS

CCDS58222.1

UniProtKB/TrEMBL

H0Y5R1

Related

ENSP00000438545.1, ENST00000546179.5

Conserved Domains (4) summary

cd00083
Location:72 → 124

HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

cd00130
Location:333 → 431

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

pfam00989
Location:144 → 250

PAS; PAS fold

pfam14598
Location:333 → 435

PAS_11; PAS domain
NM_001394524.1 → NP_001381453.1 basic helix-loop-helix ARNT-like protein 2 isoform 6

Status: REVIEWED

Source sequence(s)

AC068794, AC092829

UniProtKB/TrEMBL

H0Y5R1

Conserved Domains (3) summary

cd00130
Location:203 → 298

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

cd11469
Location:119 → 178

bHLH-PAS_ARNTL2_PASD9; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 2 (ARNTL2) and similar proteins

pfam14598
Location:381 → 483

PAS_11; PAS domain
NM_001394525.1 → NP_001381454.1 basic helix-loop-helix ARNT-like protein 2 isoform 7

Status: REVIEWED

Source sequence(s)

AC068794, AC092829

UniProtKB/TrEMBL

H0Y5R1

Conserved Domains (3) summary

cd00130
Location:189 → 284

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

cd11469
Location:106 → 164

bHLH-PAS_ARNTL2_PASD9; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 2 (ARNTL2) and similar proteins

pfam14598
Location:367 → 469

PAS_11; PAS domain
NM_001394526.1 → NP_001381455.1 basic helix-loop-helix ARNT-like protein 2 isoform 8

Status: REVIEWED

Source sequence(s)

AC068794, AC092829

Consensus CDS

CCDS91666.1

UniProtKB/TrEMBL

H0Y5R1

Related

ENSP00000442438.1, ENST00000544915.5

Conserved Domains (3) summary

cd00130
Location:158 → 253

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

cd11469
Location:74 → 133

bHLH-PAS_ARNTL2_PASD9; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 2 (ARNTL2) and similar proteins

pfam14598
Location:336 → 438

PAS_11; PAS domain
NM_001394527.1 → NP_001381456.1 basic helix-loop-helix ARNT-like protein 2 isoform 9

Status: REVIEWED

Source sequence(s)

AC068794, AC092829

UniProtKB/TrEMBL

H0Y5R1

Conserved Domains (2) summary

cd00130
Location:322 → 420

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

cd11469
Location:61 → 119

bHLH-PAS_ARNTL2_PASD9; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 2 (ARNTL2) and similar proteins
NM_001394528.1 → NP_001381457.1 basic helix-loop-helix ARNT-like protein 2 isoform 10

Status: REVIEWED

Source sequence(s)

AC068794, AC092829

UniProtKB/TrEMBL

H0Y5R1

Conserved Domains (2) summary

cd11469
Location:72 → 130

bHLH-PAS_ARNTL2_PASD9; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 2 (ARNTL2) and similar proteins

pfam14598
Location:302 → 404

PAS_11; PAS domain
NM_001394529.1 → NP_001381458.1 basic helix-loop-helix ARNT-like protein 2 isoform 11

Status: REVIEWED

Source sequence(s)

AC068794, AC092829

UniProtKB/TrEMBL

H0Y5R1

Conserved Domains (2) summary

cd00130
Location:291 → 389

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

cd11469
Location:61 → 119

bHLH-PAS_ARNTL2_PASD9; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in aryl hydrocarbon receptor nuclear translocator-like protein 2 (ARNTL2) and similar proteins
NM_020183.6 → NP_064568.3 basic helix-loop-helix ARNT-like protein 2 isoform 1

See identical proteins and their annotated locations for NP_064568.3

Status: REVIEWED

Source sequence(s)

AC068794, AC092829

Consensus CDS

CCDS8712.1

UniProtKB/Swiss-Prot

B7Z429, F5H402, Q8WYA1, Q8WYA2, Q8WYA3, Q8WYA4, Q96J63, Q9H2M4, Q9NS70, Q9NYQ4, Q9NYQ5

UniProtKB/TrEMBL

H0Y5R1

Related

ENSP00000266503.5, ENST00000266503.10

Conserved Domains (4) summary

cd00130
Location:370 → 468

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

pfam00010
Location:109 → 161

HLH; Helix-loop-helix DNA-binding domain

pfam00989
Location:181 → 287

PAS; PAS fold

pfam14598
Location:370 → 472

PAS_11; PAS domain

RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p14 Primary Assembly

Genomic

NC_000012.12 Reference GRCh38.p14 Primary Assembly

Range

27332836..27425286

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_011520768.3 → XP_011519070.1 basic helix-loop-helix ARNT-like protein 2 isoform X1

UniProtKB/TrEMBL

H0Y5R1

Conserved Domains (3) summary

cd00130
Location:350 → 448

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

pfam00010
Location:120 → 172

HLH; Helix-loop-helix DNA-binding domain

pfam14598
Location:350 → 452

PAS_11; PAS domain
XM_011520769.3 → XP_011519071.1 basic helix-loop-helix ARNT-like protein 2 isoform X2

UniProtKB/TrEMBL

H0Y5R1

Conserved Domains (4) summary

cd00130
Location:347 → 445

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

pfam00010
Location:86 → 138

HLH; Helix-loop-helix DNA-binding domain

pfam00989
Location:158 → 264

PAS; PAS fold

pfam14598
Location:347 → 449

PAS_11; PAS domain
XM_047429173.1 → XP_047285129.1 basic helix-loop-helix ARNT-like protein 2 isoform X5
XM_047429171.1 → XP_047285127.1 basic helix-loop-helix ARNT-like protein 2 isoform X3
XM_047429172.1 → XP_047285128.1 basic helix-loop-helix ARNT-like protein 2 isoform X4
XM_017019668.1 → XP_016875157.1 basic helix-loop-helix ARNT-like protein 2 isoform X6

UniProtKB/TrEMBL

H0Y5R1

Conserved Domains (4) summary

cd00083
Location:6 → 59

HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...

cd00130
Location:268 → 366

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

pfam00989
Location:79 → 185

PAS; PAS fold

pfam14598
Location:268 → 370

PAS_11; PAS domain
XM_047429174.1 → XP_047285130.1 basic helix-loop-helix ARNT-like protein 2 isoform X9
XM_006719114.3 → XP_006719177.1 basic helix-loop-helix ARNT-like protein 2 isoform X8

UniProtKB/TrEMBL

H0Y5R1

Conserved Domains (4) summary

smart00353
Location:1 → 39

HLH; helix loop helix domain

cd00130
Location:248 → 346

PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...

pfam00989
Location:59 → 165

PAS; PAS fold

pfam14598
Location:248 → 350

PAS_11; PAS domain
XM_017019669.1 → XP_016875158.1 basic helix-loop-helix ARNT-like protein 2 isoform X7

UniProtKB/TrEMBL

H0Y5R1

Alternate T2T-CHM13v2.0

Genomic

NC_060936.1 Alternate T2T-CHM13v2.0

Range

27204471..27296954

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_054372594.1 → XP_054228569.1 basic helix-loop-helix ARNT-like protein 2 isoform X1
XM_054372595.1 → XP_054228570.1 basic helix-loop-helix ARNT-like protein 2 isoform X2
XM_054372598.1 → XP_054228573.1 basic helix-loop-helix ARNT-like protein 2 isoform X5
XM_054372596.1 → XP_054228571.1 basic helix-loop-helix ARNT-like protein 2 isoform X3
XM_054372597.1 → XP_054228572.1 basic helix-loop-helix ARNT-like protein 2 isoform X4
XM_054372599.1 → XP_054228574.1 basic helix-loop-helix ARNT-like protein 2 isoform X6
XM_054372602.1 → XP_054228577.1 basic helix-loop-helix ARNT-like protein 2 isoform X9
XM_054372601.1 → XP_054228576.1 basic helix-loop-helix ARNT-like protein 2 isoform X8
XM_054372600.1 → XP_054228575.1 basic helix-loop-helix ARNT-like protein 2 isoform X7