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    Dydc2 DPY30 domain containing 2 [ Mus musculus (house mouse) ]

    Gene ID: 71200, updated on 14-May-2024

    Summary

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    Official Symbol
    Dydc2provided by MGI
    Official Full Name
    DPY30 domain containing 2provided by MGI
    Primary source
    MGI:MGI:1918450
    See related
    Ensembl:ENSMUSG00000021791 AllianceGenome:MGI:1918450
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4933428D01Rik
    Summary
    Predicted to be involved in histone H3-K4 methylation and subtelomeric heterochromatin assembly. Predicted to be part of Set1C/COMPASS complex. Orthologous to human DYDC2 (DPY30 domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 5.7) and cerebellum adult (RPKM 0.3) See more
    Orthologs
    human all
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    Genomic context

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    See Dydc2 in Genome Data Viewer
    Location:
    14 B; 14 22.36 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 14 NC_000080.7 (40770573..40795014, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 14 NC_000080.6 (41048957..41073037, complement)

    Chromosome 14 - NC_000080.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E8554 Neighboring gene predicted gene, 31839 Neighboring gene STARR-positive B cell enhancer ABC_E5429 Neighboring gene peroxiredoxin like 2A Neighboring gene STARR-seq mESC enhancer starr_36477 Neighboring gene DPY30 domain containing 1 Neighboring gene methionine adenosyltransferase 1A Neighboring gene surfactant associated protein A1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Stauber M, et al. Dev Biol, 2017 Mar 15. PMID 27914912
    2. Tissue expression patterns identify mouse cilia genes. McClintock TS, et al. Physiol Genomics, 2008 Jan 17. PMID 17971504
    3. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC130531

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    part_of Set1C/COMPASS complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    DPY30 domain-containing protein 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360608.2 → NP_001347537.1  DPY30 domain-containing protein 2

      Status: VALIDATED

      Source sequence(s)
      AC154597
      Consensus CDS
      CCDS26958.1
      UniProtKB/TrEMBL
      Q9D3X8
      Conserved Domains (1) summary
      pfam05186
      Location:1 → 42
      Dpy-30; Dpy-30 motif

    2. NM_001360609.2 → NP_001347538.1  DPY30 domain-containing protein 2

      Status: VALIDATED

      Source sequence(s)
      AC154597
      Consensus CDS
      CCDS26958.1
      UniProtKB/TrEMBL
      Q9D3X8
      Conserved Domains (1) summary
      pfam05186
      Location:1 → 42
      Dpy-30; Dpy-30 motif

    3. NM_001418551.1 → NP_001405480.1  DPY30 domain-containing protein 2

      Status: VALIDATED

      Source sequence(s)
      AC154597
      UniProtKB/TrEMBL
      Q9D3X8

    4. NM_001418552.1 → NP_001405481.1  DPY30 domain-containing protein 2

      Status: VALIDATED

      Source sequence(s)
      AC154597
      UniProtKB/TrEMBL
      Q9D3X8

    5. NM_001418553.1 → NP_001405482.1  DPY30 domain-containing protein 2

      Status: VALIDATED

      Source sequence(s)
      AC154597
      UniProtKB/TrEMBL
      Q9D3X8

    6. NM_027717.3 → NP_081993.1  DPY30 domain-containing protein 2

      See identical proteins and their annotated locations for NP_081993.1

      Status: VALIDATED

      Source sequence(s)
      AC154597
      Consensus CDS
      CCDS26958.1
      UniProtKB/TrEMBL
      Q9D3X8
      Related
      ENSMUSP00000022316.5, ENSMUST00000022316.6
      Conserved Domains (1) summary
      pfam05186
      Location:1 → 42
      Dpy-30; Dpy-30 motif

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000080.7 Reference GRCm39 C57BL/6J

      Range
      40770573..40795014 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006519559.1 → XP_006519622.1  DPY30 domain-containing protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006519622.1

      UniProtKB/TrEMBL
      Q9D3X8
      Conserved Domains (1) summary
      pfam05186
      Location:1 → 42
      Dpy-30; Dpy-30 motif
    Nucleotide Protein Strain
    Heading Accession and Version

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