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    Zfp934 zinc finger protein 934 [ Mus musculus (house mouse) ]

    Gene ID: 77117, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Zfp934provided by MGI
    Official Full Name
    zinc finger protein 934provided by MGI
    Primary source
    MGI:MGI:1924367
    See related
    Ensembl:ENSMUSG00000074865 AllianceGenome:MGI:1924367
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6720457D02Rik
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in limb mesenchyme. Orthologous to human ZNF101 (zinc finger protein 101) and ZNF699 (zinc finger protein 699). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E11.5 (RPKM 2.3), placenta adult (RPKM 1.7) and 22 other tissues See more
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    Genomic context

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    Location:
    13 B3; 13 32.74 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (62664609..62727170, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (62516795..62579321, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E7245 Neighboring gene zinc finger protein 935 Neighboring gene predicted gene, 21145 Neighboring gene STARR-seq mESC enhancer starr_34772 Neighboring gene protein C1orf43 homolog Neighboring gene STARR-seq mESC enhancer starr_34773 Neighboring gene predicted gene, 24095 Neighboring gene predicted gene, 38639 Neighboring gene zinc finger protein 1008 Neighboring gene STARR-positive B cell enhancer mm9_chr13:62725440-62725741 Neighboring gene predicted gene, 36298

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Mural RJ, et al. Science, 2002 May 31. PMID 12040188
    2. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 782

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001162911.2 → NP_001156383.1  zinc finger protein 782 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC122357, CT030240
      Consensus CDS
      CCDS88472.1
      UniProtKB/TrEMBL
      K7N6H3
      Related
      ENSMUSP00000099083.6, ENSMUST00000101547.12
      Conserved Domains (4) summary
      COG5048
      Location:178 → 471
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:359 → 379
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 44
      KRAB; KRAB box
      pfam13465
      Location:147 → 171
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001360915.1 → NP_001347844.1  zinc finger protein 782 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an exon, which results in a frameshift, compared to variant 1. The encoded isoform (3) has a shorter distinct C-terminus and lacks zinc finger domains.
      Source sequence(s)
      AC122357, BY719365
      Consensus CDS
      CCDS88471.1
      UniProtKB/TrEMBL
      A0A1Y7VKB4
      Related
      ENSMUSP00000152804.2, ENSMUST00000222746.2
      Conserved Domains (1) summary
      pfam01352
      Location:4 → 44
      KRAB; KRAB box

    3. NM_175252.5 → NP_780461.3  zinc finger protein 782 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC122357, CT030240
      Consensus CDS
      CCDS88470.1
      UniProtKB/TrEMBL
      A0A1Y7VJM8
      Related
      ENSMUSP00000152492.2, ENSMUST00000220648.2
      Conserved Domains (3) summary
      COG5048
      Location:146 → 439
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:327 → 347
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:115 → 139
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      62664609..62727170 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017315637.3 → XP_017171126.1  zinc finger protein 782 isoform X1

      Conserved Domains (4) summary
      COG5048
      Location:196 → 489
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:377 → 397
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:22 → 62
      KRAB; KRAB box
      pfam13465
      Location:165 → 189
      zf-H2C2_2; Zinc-finger double domain

    2. XM_030247464.1 → XP_030103324.1  zinc finger protein 782 isoform X3

      UniProtKB/TrEMBL
      A0A1Y7VJM8
      Conserved Domains (3) summary
      COG5048
      Location:146 → 439
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:327 → 347
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:115 → 139
      zf-H2C2_2; Zinc-finger double domain

    3. XM_030247463.2 → XP_030103323.1  zinc finger protein 782 isoform X2

      Conserved Domains (4) summary
      COG5048
      Location:183 → 476
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:364 → 384
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:9 → 49
      KRAB; KRAB box
      pfam13465
      Location:152 → 176
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version

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