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    Zfp108 zinc finger protein 108 [ Mus musculus (house mouse) ]

    Gene ID: 54678, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Zfp108provided by MGI
    Official Full Name
    zinc finger protein 108provided by MGI
    Primary source
    MGI:MGI:1891198
    See related
    Ensembl:ENSMUSG00000030486 AllianceGenome:MGI:1891198
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in eye; genitourinary system; hepatic primordium; and liver. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 1.6), cerebellum adult (RPKM 1.5) and 28 other tissues See more
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    Genomic context

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    Location:
    7 A3; 7 10.27 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (23954142..23961870)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (24254726..24262445)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 111 Neighboring gene zinc finger protein 109 Neighboring gene zinc finger protein 93 Neighboring gene STARR-seq mESC enhancer starr_18256 Neighboring gene predicted gene, 51471 Neighboring gene zinc finger protein 51 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Differential expansion of zinc-finger transcription factor loci in homologous human and mouse gene clusters. Shannon M, et al. Genome Res, 2003 Jun. PMID 12743021, Free PMC Article
    2. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    4. GUDMAP: the genitourinary developmental molecular anatomy project. McMahon AP, et al. J Am Soc Nephrol, 2008 Apr. PMID 18287559
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    General protein information

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    Preferred Names
    zinc finger protein 108

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_018791.2 → NP_061261.2  zinc finger protein 108

      See identical proteins and their annotated locations for NP_061261.2

      Status: VALIDATED

      Source sequence(s)
      AK032355, BC100339
      Consensus CDS
      CCDS85236.1
      UniProtKB/TrEMBL
      Q8CCP6
      Related
      ENSMUSP00000145928.2, ENSMUST00000206777.2
      Conserved Domains (3) summary
      COG5048
      Location:283 → 636
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:395 → 415
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:8 → 48
      KRAB; KRAB box

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      23954142..23961870
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017322372.3 → XP_017177861.1  zinc finger protein 108 isoform X1

      UniProtKB/TrEMBL
      Q8CCP6
      Related
      ENSMUSP00000145844.2, ENSMUST00000205982.2
      Conserved Domains (3) summary
      COG5048
      Location:283 → 636
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:395 → 415
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:8 → 48
      KRAB; KRAB box

    2. XM_017322373.3 → XP_017177862.1  zinc finger protein 108 isoform X1

      UniProtKB/TrEMBL
      Q8CCP6
      Conserved Domains (3) summary
      COG5048
      Location:283 → 636
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:395 → 415
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:8 → 48
      KRAB; KRAB box

    3. XM_017322374.2 → XP_017177863.1  zinc finger protein 108 isoform X1

      UniProtKB/TrEMBL
      Q8CCP6
      Conserved Domains (3) summary
      COG5048
      Location:283 → 636
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:395 → 415
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:8 → 48
      KRAB; KRAB box
    Nucleotide Protein Strain
    Heading Accession and Version

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