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    Tmem86a transmembrane protein 86A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 308602, updated on 5-Mar-2024

    Summary

    Official Symbol
    Tmem86aprovided by RGD
    Official Full Name
    transmembrane protein 86Aprovided by RGD
    Primary source
    RGD:1305749
    See related
    Ensembl:ENSRNOG00000013663 AllianceGenome:RGD:1305749
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1305749
    Summary
    Predicted to enable alkenylglycerophosphocholine hydrolase activity and alkenylglycerophosphoethanolamine hydrolase activity. Predicted to be integral component of membrane. Orthologous to human TMEM86A (transmembrane protein 86A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Adrenal (RPKM 496.7), Kidney (RPKM 277.8) and 8 other tissues See more
    Orthologs
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    Genomic context

    Location:
    1q22
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (106732168..106736518)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (97595910..97600260)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (103173032..103177382)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene SPT2 chromatin protein domain containing 1 Neighboring gene uncharacterized LOC134483110 Neighboring gene large ribosomal subunit protein eL8-like Neighboring gene immunoglobulin superfamily member 22 Neighboring gene protein tyrosine phosphatase, non-receptor type 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Markers

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables alkenylglycerophosphocholine hydrolase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    lysoplasmalogenase TMEM86A
    Names
    lysoplasmalogenase-like protein TMEM86A
    NP_001128488.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001135016.1NP_001128488.1  lysoplasmalogenase TMEM86A

      See identical proteins and their annotated locations for NP_001128488.1

      Status: VALIDATED

      Source sequence(s)
      AA924203, BE100466, BE109619, CO395066
      UniProtKB/TrEMBL
      A6JBE3, D3ZI62
      Related
      ENSRNOP00000018688.5, ENSRNOT00000018688.7
      Conserved Domains (1) summary
      pfam07947
      Location:37224
      YhhN; YhhN-like protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      106732168..106736518
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)