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    Atp6v0b ATPase H+ transporting V0 subunit B [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298451, updated on 5-Mar-2024

    Summary

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    Symbol
    Atp6v0bprovided by RGD
    Full Name
    ATPase H+ transporting V0 subunit Bprovided by RGD
    Primary source
    RGD:1308303
    See related
    AllianceGenome:RGD:1308303
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Atp6v0bl1
    Summary
    Predicted to enable proton transmembrane transporter activity. Predicted to be involved in proton transmembrane transport. Predicted to be located in endosome. Predicted to be integral component of membrane. Predicted to be part of proton-transporting V-type ATPase, V0 domain. Orthologous to human ATP6V0B (ATPase H+ transporting V0 subunit b). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Brain (RPKM 589.0), Kidney (RPKM 407.8) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Atp6v0b in Genome Data Viewer
    Location:
    5q36
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (136708823..136710339, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (131423384..131424900, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (136718352..136719868, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 6 member 9 Neighboring gene coiled-coil domain containing 24 Neighboring gene uncharacterized LOC120102957 Neighboring gene beta-1,4-galactosyltransferase 2 Neighboring gene diphthamide biosynthesis 2 Neighboring gene importin 13

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Mouse Atp6f, the gene encoding the 23-kDa proteolipid of vacuolar proton translocating ATPase. Sun-Wada GH, et al. Gene, 2001 Aug 22. PMID 11675001
    2. Expression and localization of the mouse homologue of the yeast V-ATPase 21-kDa Subunit c" (Vma16p). Nishi T, et al. J Biol Chem, 2001 Sep 7. PMID 11441017
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables proton-transporting ATPase activity, rotational mechanism IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in clathrin-coated vesicle membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endosome ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of proton-transporting V-type ATPase complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    part_of proton-transporting V-type ATPase, V0 domain IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transmembrane transporter complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    V-type proton ATPase 21 kDa proteolipid subunit c''
    Names
    ATPase, H+ transporting, lysosomal 21kDa, V0 subunit b
    ATPase, H+ transporting, lysosomal V0 subunit B
    ATPase, H+ transporting, lysosomal V0 subunit B-like 1
    V-type proton ATPase 21 kDa proteolipid subunit
    NP_001100151.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001106681.1 → NP_001100151.1  V-type proton ATPase 21 kDa proteolipid subunit c''

      See identical proteins and their annotated locations for NP_001100151.1

      Status: PROVISIONAL

      Source sequence(s)
      CH474008
      UniProtKB/TrEMBL
      A6JZF2
      Conserved Domains (1) summary
      pfam00137
      Location:31 → 91
      ATP-synt_C; ATP synthase subunit C

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      136708823..136710339 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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