Slc35b1 solute carrier family 35, member B1 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Slc35b1provided by RGD
Official Full Name: solute carrier family 35, member B1provided by RGD
Primary source: RGD:727783
See related: Ensembl:ENSRNOG00000004510 AllianceGenome:RGD:727783
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: AXER; UGTrel1
Summary: Predicted to enable UDP-galactose transmembrane transporter activity and UDP-glucose transmembrane transporter activity. Predicted to be involved in UDP-galactose transmembrane transport. Predicted to be integral component of membrane. Predicted to be integral component of Golgi membrane and integral component of endoplasmic reticulum membrane. Orthologous to human SLC35B1 (solute carrier family 35 member B1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 278.0), Kidney (RPKM 275.8) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 10q26

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	10	NC_086028.1 (80824972..80832048)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	10	NC_051345.1 (80327921..80335279)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	10	NC_005109.4 (83201532..83208605)

Chromosome 10 - NC_086028.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

Slc35b1 (e-PCR), detects polymorphism
- UniSTS:546007

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables ATP:ADP antiporter activity	IEA Inferred from Electronic Annotation more info
enables ATP:ADP antiporter activity	ISO Inferred from Sequence Orthology more info
enables UDP-galactose transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info
enables UDP-glucose transmembrane transporter activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in ADP transport	IEA Inferred from Electronic Annotation more info
involved_in ATP transport	IEA Inferred from Electronic Annotation more info
involved_in UDP-galactose transmembrane transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in UDP-glucose transmembrane transport	IEA Inferred from Electronic Annotation more info
involved_in transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in Golgi membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: solute carrier family 35 member B1

Names: ATP/ADP exchanger ER; UDP-galactose transporter-related protein 1; endoplasmic reticulum ATP/ADP translocase; galactose transporter

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_199081.1 → NP_954512.1 solute carrier family 35 member B1

See identical proteins and their annotated locations for NP_954512.1

Status: PROVISIONAL

Source sequence(s)

AY349135

UniProtKB/Swiss-Prot

P70639, Q6V7K3

UniProtKB/TrEMBL

A0A8I6ADT8

Related

ENSRNOP00000006179.3, ENSRNOT00000006179.5

Conserved Domains (1) summary

pfam08449
Location:16 → 309

UAA; UAA transporter family

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086028.1 Reference GRCr8

Range

80824972..80832048

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_039085590.2 → XP_038941518.1 solute carrier family 35 member B1 isoform X2

Conserved Domains (1) summary

pfam08449
Location:1 → 212

UAA; UAA transporter family
XM_039085591.2 → XP_038941519.1 solute carrier family 35 member B1 isoform X1

Conserved Domains (1) summary

pfam08449
Location:1 → 185

UAA; UAA transporter family