CCL21 C-C motif chemokine ligand 21 [Macaca mulatta (Rhesus monkey)] - Gene

Summary

Official Symbol: CCL21provided by VGNC
Official Full Name: C-C motif chemokine ligand 21provided by VGNC
Primary source: VGNC:VGNC:104885
See related: Ensembl:ENSMMUG00000063081
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Macaca mulatta
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 15

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
103	current	Mmul_10 (GCF_003339765.1)	15	NC_041768.1 (49487673..49488338)
102	previous assembly	Mmul_8.0.1 (GCF_000772875.2)	15	NC_027907.1 (49551343..49552008)

Chromosome 15 - NC_041768.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables CCR chemokine receptor binding	IEA Inferred from Electronic Annotation more info	PubMed
enables chemokine activity	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in G protein-coupled receptor signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to interleukin-1	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to tumor necrosis factor	IEA Inferred from Electronic Annotation more info	PubMed
involved_in cellular response to type II interferon	IEA Inferred from Electronic Annotation more info	PubMed
involved_in chemokine-mediated signaling pathway	IEA Inferred from Electronic Annotation more info	PubMed
involved_in immune response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in inflammatory response	IEA Inferred from Electronic Annotation more info	PubMed
involved_in lymphocyte chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in monocyte chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in neutrophil chemotaxis	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of ERK1 and ERK2 cascade	IEA Inferred from Electronic Annotation more info	PubMed
involved_in positive regulation of GTPase activity	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in extracellular region	IEA Inferred from Electronic Annotation more info	PubMed
located_in extracellular space	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: C-C motif chemokine 21

Names: chemokine CCL21/6CKINE; small-inducible cytokine A21

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001032855.1 → NP_001028027.1 C-C motif chemokine 21 precursor

See identical proteins and their annotated locations for NP_001028027.1

Status: PROVISIONAL

Source sequence(s)

AF449275

UniProtKB/Swiss-Prot

Q8HYP5

UniProtKB/TrEMBL

G7NFF7

Related

ENSMMUP00000070168.1, ENSMMUT00000082253.1

Conserved Domains (1) summary

cd01119
Location:29 → 91

Chemokine_CC_DCCL; subgroup of the Chemokine_CC subgroup based on the presence of a DCCL motif involving the two N-terminal cysteine residues; includes a number of small inducible cytokines capable of reversibly inhibiting normal hematopoietic progenitor proliferation by ...