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    Rps10 ribosomal protein S10 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 81773, updated on 13-Apr-2024

    Summary

    Official Symbol
    Rps10provided by RGD
    Official Full Name
    ribosomal protein S10provided by RGD
    Primary source
    RGD:621024
    See related
    Ensembl:ENSRNOG00000000490 AllianceGenome:RGD:621024
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables tRNA binding activity. A structural constituent of ribosome. Involved in ribosomal small subunit assembly. Part of cytosolic small ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 9. Orthologous to human RPS10 (ribosomal protein S10). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Spleen (RPKM 2232.9), Thymus (RPKM 2112.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rps10 in Genome Data Viewer
    Location:
    20p12
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (5696135..5700863, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (5694313..5698922, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (7215762..7220331, complement)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene small integral membrane protein 29 Neighboring gene nudix hydrolase 3 Neighboring gene protein kinase C and casein kinase substrate in neurons 1 Neighboring gene SAM pointed domain containing ets transcription factor

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    enables tRNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in ribosomal small subunit assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic small ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of cytosolic small ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in synapse ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    small ribosomal subunit protein eS10
    Names
    40S ribosomal protein S10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031109.2NP_112371.1  small ribosomal subunit protein eS10

      See identical proteins and their annotated locations for NP_112371.1

      Status: VALIDATED

      Source sequence(s)
      FM057870, JAXUCZ010000020
      UniProtKB/Swiss-Prot
      P63326
      UniProtKB/TrEMBL
      A6JJM8, D3ZCN9
      Related
      ENSRNOP00000077780.1, ENSRNOT00000107117.1
      Conserved Domains (1) summary
      pfam03501
      Location:397
      S10_plectin; Plectin/S10 domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      5696135..5700863 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063279576.1XP_063135646.1  small ribosomal subunit protein eS10 isoform X1

    2. XM_063279577.1XP_063135647.1  small ribosomal subunit protein eS10 isoform X2