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    Mex3a mex-3 RNA binding family member A [ Rattus norvegicus (Norway rat) ]

    Gene ID: 310631, updated on 30-Mar-2024

    Summary

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    Official Symbol
    Mex3aprovided by RGD
    Official Full Name
    mex-3 RNA binding family member Aprovided by RGD
    Primary source
    RGD:1564904
    See related
    Ensembl:ENSRNOG00000058654 AllianceGenome:RGD:1564904
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1564904
    Summary
    Predicted to enable RNA binding activity. Predicted to be located in P-body and cytosol. Orthologous to human MEX3A (mex-3 RNA binding family member A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Thymus (RPKM 31.8), Uterus (RPKM 17.1) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    Location:
    2q34
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (176287900..176297369)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (173990098..173999567)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (187893678..187902546)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene lamin A/C Neighboring gene uncharacterized LOC120100862 Neighboring gene RAB25, member RAS oncogene family Neighboring gene late endosomal/lysosomal adaptor, MAPK and MTOR activator 2 Neighboring gene ubiquilin 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts. Baltz AG, et al. Mol Cell, 2012 Jun 8. PMID 22681889

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in P-body ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RNA-binding protein MEX3A
    Names
    mex3 homolog A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001398739.1 → NP_001385668.1  RNA-binding protein MEX3A

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/TrEMBL
      A0A1B0GWR7
      Related
      ENSRNOP00000075996.2, ENSRNOT00000093014.2
      Conserved Domains (3) summary
      cd16518
      Location:469 → 509
      RING-HC_MEX3; RING finger, HC subclass, found in RNA-binding proteins of the evolutionarily-conserved MEX-3 family
      cd22423
      Location:132 → 204
      KH-I_MEX3_rpt1; first type I K homology (KH) RNA-binding domain found in the family of MEX-3 RNA-binding proteins
      cd22424
      Location:221 → 292
      KH-I_MEX3_rpt2; second type I K homology (KH) RNA-binding domain found in the family of MEX-3 RNA-binding proteins

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      176287900..176297369
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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