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    Adgrg3 adhesion G protein-coupled receptor G3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 291854, updated on 11-Apr-2024

    Summary

    Official Symbol
    Adgrg3provided by RGD
    Official Full Name
    adhesion G protein-coupled receptor G3provided by RGD
    Primary source
    RGD:1305674
    See related
    Ensembl:ENSRNOG00000014896 AllianceGenome:RGD:1305674
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Gpr97
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in several processes, including adenylate cyclase-activating G protein-coupled receptor signaling pathway; negative regulation of CREB transcription factor activity; and negative regulation of NIK/NF-kappaB signaling. Predicted to be located in plasma membrane. Predicted to be integral component of plasma membrane. Orthologous to human ADGRG3 (adhesion G protein-coupled receptor G3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Kidney (RPKM 11.6), Spleen (RPKM 8.4) and 8 other tissues See more
    Orthologs
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    Genomic context

    Location:
    19p13
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 19 NC_086037.1 (9978450..10007145, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 19 NC_051354.1 (9972425..10001118, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 19 NC_005118.4 (10392001..10422606, complement)

    Chromosome 19 - NC_086037.1Genomic Context describing neighboring genes Neighboring gene katanin regulatory subunit B1 Neighboring gene dynein regulatory complex subunit 7 Neighboring gene adhesion G protein-coupled receptor G1 Neighboring gene adhesion G protein-coupled receptor G5

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General protein information

    Preferred Names
    probable G-protein coupled receptor 97; adhesion G protein-coupled receptor G3
    Names
    G protein-coupled receptor 97

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086037.1 Reference GRCr8

      Range
      9978450..10007145 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006255127.5XP_006255189.1  adhesion G protein-coupled receptor G3 isoform X4

      See identical proteins and their annotated locations for XP_006255189.1

      UniProtKB/TrEMBL
      A6JY31
      Conserved Domains (2) summary
      pfam01825
      Location:167206
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:216465
      7tm_4; Olfactory receptor
    2. XM_006255126.5XP_006255188.1  adhesion G protein-coupled receptor G3 isoform X2

      See identical proteins and their annotated locations for XP_006255188.1

      UniProtKB/TrEMBL
      A0A0G2JSN6, A6JY31
      Related
      ENSRNOP00000020062.5
      Conserved Domains (2) summary
      pfam01825
      Location:216255
      GPS; GPCR proteolysis site, GPS, motif
      cl21561
      Location:265514
      7tm_4; Olfactory receptor
    3. XM_039098149.1XP_038954077.1  adhesion G protein-coupled receptor G3 isoform X3

      UniProtKB/TrEMBL
      A6JY31
      Conserved Domains (3) summary
      pfam01825
      Location:195233
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:245270
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:243502
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    4. XM_039098148.1XP_038954076.1  adhesion G protein-coupled receptor G3 isoform X1

      UniProtKB/TrEMBL
      A6JY31
      Conserved Domains (3) summary
      pfam01825
      Location:244282
      GPS; GPCR proteolysis site, GPS, motif
      cd14964
      Location:294319
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:292551
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily