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    Odr4 odr4 GPCR localization factor homolog [ Mus musculus (house mouse) ]

    Gene ID: 226499, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Odr4provided by MGI
    Official Full Name
    odr4 GPCR localization factor homologprovided by MGI
    Primary source
    MGI:MGI:2385108
    See related
    Ensembl:ENSMUSG00000006010 AllianceGenome:MGI:2385108
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    odr-4; 1810053E15Rik
    Summary
    Predicted to be involved in protein localization. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including choroid invagination; craniocervical region bone; embryo mesenchyme; meninges; and sensory organ. Orthologous to human ODR4 (odr-4 GPCR localization factor homolog). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in bladder adult (RPKM 12.0), frontal lobe adult (RPKM 8.4) and 25 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    1 G1; 1 63.84 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (150237056..150268831, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (150361305..150393080, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene protein BEX4-like Neighboring gene STARR-seq mESC enhancer starr_02598 Neighboring gene RIKEN cDNA 2310030A07 gene Neighboring gene STARR-seq mESC enhancer starr_02599 Neighboring gene phosducin Neighboring gene STARR-positive B cell enhancer mm9_chr1:152220093-152220393 Neighboring gene STARR-positive B cell enhancer ABC_E4355 Neighboring gene STARR-positive B cell enhancer ABC_E9061 Neighboring gene STARR-positive B cell enhancer ABC_E2013 Neighboring gene STARR-seq mESC enhancer starr_02600 Neighboring gene translocated promoter region, nuclear basket protein Neighboring gene STARR-seq mESC enhancer starr_02601 Neighboring gene proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein) Neighboring gene predicted gene, 41967

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of transcripts with enriched expression in the developing and adult pancreas. Hoffman BG, et al. Genome Biol, 2008. PMID 18554416, Free PMC Article
    2. Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors. Kim H, et al. Cell, 2018 Dec 13. PMID 30550785, Free PMC Article
    3. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Clone Names

    • MGC7150

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein odr-4 homolog
    Names
    mODR-4
    olfactory specific odr-4
    NP_001070705.1
    NP_001344508.1
    NP_663486.2
    XP_036019881.1
    XP_036019882.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001077237.1 → NP_001070705.1  protein odr-4 homolog isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1. The resulting protein (isoform 2) is shorter than isoform 1.
      Source sequence(s)
      AC121113, AK152022, BE134939, BY247764, CB235715
      Consensus CDS
      CCDS35733.1
      UniProtKB/Swiss-Prot
      Q4PJX1
      Related
      ENSMUSP00000095153.4, ENSMUST00000097547.10
      Conserved Domains (1) summary
      pfam14778
      Location:28 → 347
      ODR4-like; Olfactory receptor 4-like

    2. NM_001357579.1 → NP_001344508.1  protein odr-4 homolog isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC121113, AC161432
      Conserved Domains (1) summary
      pfam14778
      Location:1 → 298
      ODR4-like; Olfactory receptor 4-like

    3. NM_145511.2 → NP_663486.2  protein odr-4 homolog isoform 1

      See identical proteins and their annotated locations for NP_663486.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC121113, AK152022, BE134939, BY247764, CB235715, CX243768
      Consensus CDS
      CCDS15355.2
      UniProtKB/Swiss-Prot
      Q3U8Y3, Q4PJX1, Q99J66
      Related
      ENSMUSP00000107544.3, ENSMUST00000111913.9
      Conserved Domains (1) summary
      pfam14778
      Location:28 → 379
      ODR4-like; Olfactory receptor 4-like

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      150237056..150268831 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163989.1 → XP_036019882.1  protein odr-4 homolog isoform X2

      Conserved Domains (1) summary
      pfam14778
      Location:1 → 250
      ODR4-like; Olfactory receptor 4-like

    2. XM_036163988.1 → XP_036019881.1  protein odr-4 homolog isoform X1

      Conserved Domains (1) summary
      pfam14778
      Location:28 → 331
      ODR4-like; Olfactory receptor 4-like
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4PJX1.2 GenPept UniProtKB/Swiss-Prot:Q4PJX1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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