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    Ovgp1 oviductal glycoprotein 1 [ Mus musculus (house mouse) ]

    Gene ID: 12659, updated on 11-Apr-2024

    Summary

    Official Symbol
    Ovgp1provided by MGI
    Official Full Name
    oviductal glycoprotein 1provided by MGI
    Primary source
    MGI:MGI:106661
    See related
    Ensembl:ENSMUSG00000074340 AllianceGenome:MGI:106661
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    OGP; MOGP; muc9; Chit5; 120kDa
    Summary
    Predicted to enable chitin binding activity and chitinase activity. Acts upstream of or within negative regulation of binding activity of sperm to zona pellucida. Located in egg coat and perivitelline space. Is expressed in oviduct and testis. Orthologous to human OVGP1 (oviductal glycoprotein 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in ovary adult (RPKM 257.8) and testis adult (RPKM 8.3) See more
    Orthologs
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    Genomic context

    See Ovgp1 in Genome Data Viewer
    Location:
    3 F2.2; 3 46.46 cM
    Exon count:
    11
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (105881118..105894739)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (105973802..105987423)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene ATP synthase peripheral stalk-membrane subunit b Neighboring gene WD repeat domain 77 Neighboring gene STARR-positive B cell enhancer ABC_E6099 Neighboring gene STARR-seq mESC enhancer starr_08642 Neighboring gene ciliary microtubule associated protein 3 Neighboring gene predicted gene 42722 Neighboring gene chitinase-like 5

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3)  1 citation
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General gene information

    Markers

    Potential readthrough

    Included gene: Wdr77

    Clone Names

    • MGC169619

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables chitin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables chitinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in egg coat IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in extracellular region IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in microtubule cytoskeleton ISO
    Inferred from Sequence Orthology
    more info
     
    located_in perivitelline space IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    oviduct-specific glycoprotein
    Names
    chitinase 5
    estrogen-dependent oviduct protein
    mucin 9
    oviduct glycoprotein OGP
    oviductal glycoprotein 1, 120kD
    oviductin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_007696.2NP_031722.1  oviduct-specific glycoprotein precursor

      See identical proteins and their annotated locations for NP_031722.1

      Status: PROVISIONAL

      Source sequence(s)
      D32137
      Consensus CDS
      CCDS17716.1
      UniProtKB/Swiss-Prot
      Q62010
      UniProtKB/TrEMBL
      B9EHI6, Q54AJ4, Q5GJ02
      Related
      ENSMUSP00000000573.3, ENSMUST00000000573.9
      Conserved Domains (2) summary
      cd02872
      Location:24382
      GH18_chitolectin_chitotriosidase; This conserved domain family includes a large number of catalytically inactive chitinase-like lectins (chitolectins) including YKL-39, YKL-40 (HCGP39), YM1, oviductin, and AMCase (acidic mammalian chitinase), as well as catalytically active ...
      smart00636
      Location:23360
      Glyco_18; Glyco_18 domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      105881118..105894739
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)