Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Cd5l CD5 antigen-like [ Mus musculus (house mouse) ]

    Gene ID: 11801, updated on 9-Jan-2022

    Summary

    Official Symbol
    Cd5lprovided by MGI
    Official Full Name
    CD5 antigen-likeprovided by MGI
    Primary source
    MGI:MGI:1334419
    See related
    Ensembl:ENSMUSG00000015854
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1/6; AIM; CT2; Pdp; Api6; mAIM; AAC-11; AI047839; Sp-alpha
    Summary
    Predicted to enable serine-type endopeptidase activity. Acts upstream of or within positive regulation of complement-dependent cytotoxicity and regulation of complement activation. Located in cell surface and plasma membrane. Is expressed in central nervous system; liver; retina; stomach; and testis. Orthologous to human CD5L (CD5 molecule like). [provided by Alliance of Genome Resources, Nov 2021]
    Expression
    Biased expression in liver E18 (RPKM 55.6), liver E14 (RPKM 35.5) and 4 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Cd5l in Genome Data Viewer
    Location:
    3; 3 F1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (87265188..87278381)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (87357881..87371074)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (87161803..87174996)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene Fc receptor-like S, scavenger receptor Neighboring gene predicted gene, 31879 Neighboring gene predicted gene, 31940 Neighboring gene Fc receptor-like 1 Neighboring gene predicted gene, 40084

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables scavenger receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables serine-type endopeptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cell surface IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell surface ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    CD5 antigen-like
    Names
    AIM/Spalpha
    CT-2
    Pdp 1/6
    apoptosis inhibitor 6
    apoptosis inhibitor expressed by macrophages

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009690.2NP_033820.2  CD5 antigen-like precursor

      See identical proteins and their annotated locations for NP_033820.2

      Status: VALIDATED

      Source sequence(s)
      AK159181, BY582711
      Consensus CDS
      CCDS17451.1
      UniProtKB/Swiss-Prot
      Q9QWK4
      Related
      ENSMUSP00000015998.7, ENSMUST00000015998.8
      Conserved Domains (2) summary
      smart00202
      Location:246348
      SR; Scavenger receptor Cys-rich
      pfam00530
      Location:251348
      SRCR; Scavenger receptor cysteine-rich domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      87265188..87278381
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center