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    Mup5 major urinary protein 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 298107, updated on 13-Apr-2024

    Summary

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    Official Symbol
    Mup5provided by RGD
    Official Full Name
    major urinary protein 5provided by RGD
    Primary source
    RGD:735107
    See related
    Ensembl:ENSRNOG00000067602 AllianceGenome:RGD:735107
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    PGCL6
    Summary
    Predicted to enable pheromone binding activity and small molecule binding activity. Predicted to be involved in negative regulation of endopeptidase activity. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward (RPKM 14142.4) See more
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    Genomic context

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    Location:
    5q24
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 5 NC_086023.1 (79996023..79999893, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 5 NC_051340.1 (75201324..75204903, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 5 NC_005104.4 (77744217..77903161, complement)

    Chromosome 5 - NC_086023.1Genomic Context describing neighboring genes Neighboring gene major urinary protein 4, pseudogene 8 Neighboring gene major urinary protein-like Neighboring gene zinc finger protein 37-like Neighboring gene major urinary protein-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. The evolutionary history of the SAL1 gene family in eutherian mammals. Meslin C, et al. BMC Evol Biol, 2011 May 28. PMID 21619679, Free PMC Article
    2. Molecular evidence of complex tissue- and sex-specific mRNA expression of the rat alpha(2u)-globulin multigene family. Saito K, et al. Biochem Biophys Res Commun, 2000 Jun 7. PMID 10833415
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables endopeptidase inhibitor activity NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables pheromone binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables small molecule binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    major urinary protein 5
    Names
    alpha-2u globulin PGCL5
    alpha-2u globulin PGCL6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_203325.2 → NP_976070.2  major urinary protein 5 precursor

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000005
      UniProtKB/TrEMBL
      A6KDY3
      Related
      ENSRNOP00000093267.1, ENSRNOT00000116257.1

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086023.1 Reference GRCr8

      Range
      79996023..79999893 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039109478.2 → XP_038965406.1  major urinary protein 5 isoform X1

      UniProtKB/TrEMBL
      A0A8I6AJN1, Q9JJI1
      Conserved Domains (1) summary
      cd19428
      Location:69 → 224
      lipocalin_MUP-like; major urinary proteins (MUPs) and similar proteins

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_147213.1: Suppressed sequence

      Description
      NM_147213.1: This RefSeq was removed because it is redundant with another RefSeq.
    Nucleotide Protein Strain
    Heading Accession and Version

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