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    JCHAIN joining chain of multimeric IgA and IgM [ Homo sapiens (human) ]

    Gene ID: 3512, updated on 8-Jul-2021

    Summary

    Official Symbol
    JCHAINprovided by HGNC
    Official Full Name
    joining chain of multimeric IgA and IgMprovided by HGNC
    Primary source
    HGNC:HGNC:5713
    See related
    Ensembl:ENSG00000132465 MIM:147790
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    IGJ; JCH; IGCJ
    Expression
    Biased expression in colon (RPKM 2264.9), duodenum (RPKM 2014.1) and 10 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See JCHAIN in Genome Data Viewer
    Location:
    4q13.3
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) 4 NC_000004.12 (70655541..70666508, complement)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (71521258..71532225, complement)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene ameloblastin Neighboring gene enamelin Neighboring gene uncharacterized LOC101927297 Neighboring gene UTP3 small subunit processome component

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    General protein information

    Preferred Names
    immunoglobulin J chain
    Names
    IgJ chain
    J chain
    immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144646.4NP_653247.1  immunoglobulin J chain precursor

      See identical proteins and their annotated locations for NP_653247.1

      Status: VALIDATED

      Source sequence(s)
      BC038982, BP221304, BP418109
      Consensus CDS
      CCDS3545.1
      UniProtKB/Swiss-Prot
      P01591
      Related
      ENSP00000254801.4, ENST00000254801.9
      Conserved Domains (1) summary
      pfam15097
      Location:24159
      Ig_J_chain; Immunoglobulin J chain

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p13 Primary Assembly

      Range
      70655541..70666508 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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