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    Sfxn1 sideroflexin 1 [ Mus musculus (house mouse) ]

    Gene ID: 14057, updated on 6-May-2021

    Summary

    Official Symbol
    Sfxn1provided by MGI
    Official Full Name
    sideroflexin 1provided by MGI
    Primary source
    MGI:MGI:2137677
    See related
    Ensembl:ENSMUSG00000021474
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    f; 2810002O05Rik; A930015P12Rik
    Expression
    Ubiquitous expression in kidney adult (RPKM 32.7), large intestine adult (RPKM 19.7) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Sfxn1 in Genome Data Viewer
    Location:
    13 B1; 13 28.4 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (54225675..54262365)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (54071656..54108346)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 13 NC_000079.5 (54167214..54203715)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 34557 Neighboring gene dopamine receptor D1 Neighboring gene ribosomal protein, large, P0 pseudogene Neighboring gene predicted gene, 34640

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Spontaneous (1) 
    • Gene trapped (1) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables D-serine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables L-serine transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables serine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in D-serine transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in L-serine transport ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within amino acid transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within erythrocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within iron ion transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within iron ion transport TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in mitochondrial transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of one-carbon metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in serine import into mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in serine import into mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    sideroflexin-1
    Names
    flexed tail

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027324.5NP_081600.1  sideroflexin-1

      See identical proteins and their annotated locations for NP_081600.1

      Status: VALIDATED

      Source sequence(s)
      AC163343, AK151110, CT030176
      Consensus CDS
      CCDS26525.1
      UniProtKB/Swiss-Prot
      Q99JR1
      Related
      ENSMUSP00000021930.9, ENSMUST00000021930.10
      Conserved Domains (1) summary
      pfam03820
      Location:16322
      Mtc; Tricarboxylate carrier

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      54225675..54262365
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516849.5XP_006516912.2  sideroflexin-1 isoform X1

      See identical proteins and their annotated locations for XP_006516912.2

      UniProtKB/Swiss-Prot
      Q99JR1
      Conserved Domains (1) summary
      pfam03820
      Location:16322
      Mtc; Tricarboxylate carrier
    2. XM_006516850.5XP_006516913.1  sideroflexin-1 isoform X1

      See identical proteins and their annotated locations for XP_006516913.1

      UniProtKB/Swiss-Prot
      Q99JR1
      Conserved Domains (1) summary
      pfam03820
      Location:16322
      Mtc; Tricarboxylate carrier

    RNA

    1. XR_003950425.1 RNA Sequence

    2. XR_004937937.1 RNA Sequence

    3. XR_003950424.2 RNA Sequence

    4. XR_004937936.1 RNA Sequence

    5. XR_004937939.1 RNA Sequence

    6. XR_004937938.1 RNA Sequence

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