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    Mrgprh MAS-related GPR, member H [ Mus musculus (house mouse) ]

    Gene ID: 80978, updated on 21-Apr-2024

    Summary

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    Official Symbol
    Mrgprhprovided by MGI
    Official Full Name
    MAS-related GPR, member Hprovided by MGI
    Primary source
    MGI:MGI:1934134
    See related
    Ensembl:ENSMUSG00000059408 AllianceGenome:MGI:1934134
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mgrb; MrgH; Gpr90
    Summary
    Predicted to enable angiotensin receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within signal transduction. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    Location:
    17 A1; 17 8.7 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (13094921..13096729)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (12876034..12877842)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene antisense Igf2r RNA Neighboring gene ribosomal protein L41 pseudogene Neighboring gene MAS1 oncogene Neighboring gene predicted gene, 53988 Neighboring gene poly(A)-specific ribonuclease (PARN)-like domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E2471 Neighboring gene mitochondrial ribosomal protein L18 Neighboring gene t-complex protein 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. An expressed sequence tag (EST) data mining strategy succeeding in the discovery of new G-protein coupled receptors. Wittenberger T, et al. J Mol Biol, 2001 Mar 30. PMID 11273702
    2. Orphan G protein-coupled receptors MrgA1 and MrgC11 are distinctively activated by RF-amide-related peptides through the Galpha q/11 pathway. Han SK, et al. Proc Natl Acad Sci U S A, 2002 Nov 12. PMID 12397184, Free PMC Article
    3. A diverse family of GPCRs expressed in specific subsets of nociceptive sensory neurons. Dong X, et al. Cell, 2001 Sep 7. PMID 11551509
    4. Atypical expansion in mice of the sensory neuron-specific Mrg G protein-coupled receptor family. Zylka MJ, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12909716, Free PMC Article
    5. Comparative genomic analysis of eutherian Mas-related G protein-coupled receptor genes. Premzl M. Gene, 2014 Apr 25. PMID 24583173

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (1) 

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables angiotensin receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    mas-related G-protein coupled receptor member H
    Names
    G protein-coupled receptor 90
    G-protein coupled receptor GPR90
    Mas-related G protein-coupled receptor b

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_030726.1 → NP_109651.1  mas-related G-protein coupled receptor member H

      See identical proteins and their annotated locations for NP_109651.1

      Status: PROVISIONAL

      Source sequence(s)
      AF295365
      Consensus CDS
      CCDS28395.1
      UniProtKB/Swiss-Prot
      Q149S2, Q99MT8
      UniProtKB/TrEMBL
      W8W3M0
      Related
      ENSMUSP00000074768.3, ENSMUST00000075296.4
      Conserved Domains (2) summary
      pfam00001
      Location:51 → 279
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:42 → 215
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      13094921..13096729
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q99MT8.1 GenPept UniProtKB/Swiss-Prot:Q99MT8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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