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    Cdc26 cell division cycle 26 [ Mus musculus (house mouse) ]

    Gene ID: 66440, updated on 5-Mar-2024

    Summary

    Official Symbol
    Cdc26provided by MGI
    Official Full Name
    cell division cycle 26provided by MGI
    Primary source
    MGI:MGI:1913690
    See related
    Ensembl:ENSMUSG00000066149 AllianceGenome:MGI:1913690
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2010012C09Rik
    Summary
    Predicted to be involved in protein K11-linked ubiquitination and regulation of mitotic cell cycle. Predicted to act upstream of or within cell division. Predicted to be located in nucleus. Predicted to be part of anaphase-promoting complex. Is expressed in pancreas epithelium. Orthologous to human CDC26 (cell division cycle 26). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 20.0), limb E14.5 (RPKM 16.2) and 27 other tissues See more
    Orthologs
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    Genomic context

    Location:
    4 B3; 4 33.12 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (62310581..62326862, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (62392344..62408625, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene solute carrier family 31, member 2 Neighboring gene FK506 binding protein 15 Neighboring gene STARR-seq mESC enhancer starr_10422 Neighboring gene STARR-positive B cell enhancer ABC_E1277 Neighboring gene STARR-seq mESC enhancer starr_10423 Neighboring gene solute carrier family 31, member 1 Neighboring gene STARR-positive B cell enhancer mm9_chr4:62069546-62069847 Neighboring gene pre-mRNA processing factor 4 Neighboring gene ring finger protein 183 Neighboring gene predicted gene, 30589

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC130281

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in anaphase-promoting complex-dependent catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein K11-linked ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein K11-linked ubiquitination ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of mitotic cell cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of anaphase-promoting complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of anaphase-promoting complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    anaphase-promoting complex subunit CDC26
    Names
    CDC26 subunit of anaphase promoting complex
    cell division cycle protein 26 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001368241.1NP_001355170.1  anaphase-promoting complex subunit CDC26

      Status: VALIDATED

      Source sequence(s)
      AL732548
      Consensus CDS
      CCDS38774.1
      UniProtKB/Swiss-Prot
      Q99JP4
      Related
      ENSMUSP00000103083.2, ENSMUST00000107459.2
    2. NM_139291.4NP_647452.1  anaphase-promoting complex subunit CDC26

      See identical proteins and their annotated locations for NP_647452.1

      Status: VALIDATED

      Source sequence(s)
      AL732548
      Consensus CDS
      CCDS38774.1
      UniProtKB/Swiss-Prot
      Q99JP4
      Related
      ENSMUSP00000081573.6, ENSMUST00000084525.12
      Conserved Domains (1) summary
      pfam10471
      Location:160
      ANAPC_CDC26; Anaphase-promoting complex APC subunit CDC26

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      62310581..62326862 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)