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    Abhd18 abhydrolase domain containing 18 [ Mus musculus (house mouse) ]

    Gene ID: 269423, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Abhd18provided by MGI
    Official Full Name
    abhydrolase domain containing 18provided by MGI
    Primary source
    MGI:MGI:1915468
    See related
    Ensembl:ENSMUSG00000037818 AllianceGenome:MGI:1915468
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2310068E01Rik; 3110057O12Rik
    Summary
    Predicted to be located in extracellular region. Is expressed in dorsal root ganglion. Orthologous to human ABHD18 (abhydrolase domain containing 18). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in heart adult (RPKM 6.0), frontal lobe adult (RPKM 3.4) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    3 B; 3 19.58 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (40825532..40892573)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (40871095..40938138)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene major facilitator superfamily domain containing 8 Neighboring gene STARR-positive B cell enhancer ABC_E1617 Neighboring gene predicted gene 2011 Neighboring gene FUN14 domain containing 2 pseudogene Neighboring gene RIKEN cDNA 6430590A07 gene Neighboring gene FUN14 domain containing 2B Neighboring gene STARR-positive B cell enhancer ABC_E7910 Neighboring gene STARR-seq mESC enhancer starr_07475 Neighboring gene La ribonucleoprotein 1B Neighboring gene predicted gene, 22043 Neighboring gene predicted gene 42437

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    2. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Markers

    Homology

    Clone Names

    • 4732404H23

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein ABHD18
    Names
    abhydrolase domain-containing protein 18
    alpha/beta hydrolase domain-containing protein 18

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001377110.1 → NP_001364039.1  protein ABHD18 isoform b

      Status: VALIDATED

      Source sequence(s)
      AC160757
      UniProtKB/TrEMBL
      B7ZNF5
      Conserved Domains (1) summary
      pfam09752
      Location:1 → 381
      DUF2048; Abhydrolase domain containing 18

    2. NM_001377111.1 → NP_001364040.1  protein ABHD18 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3), as well as variant 4, encodes isoform c.
      Source sequence(s)
      AC160757
      UniProtKB/TrEMBL
      B7ZNF5
      Conserved Domains (1) summary
      cl21494
      Location:1 → 330
      Abhydrolase; alpha/beta hydrolases

    3. NM_001377112.1 → NP_001364041.1  protein ABHD18 isoform c

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4), as well as variant 3, encodes isoform c.
      Source sequence(s)
      AC160757
      UniProtKB/TrEMBL
      B7ZNF5
      Conserved Domains (1) summary
      cl21494
      Location:1 → 330
      Abhydrolase; alpha/beta hydrolases

    4. NM_026622.4 → NP_080898.2  protein ABHD18 isoform a precursor

      See identical proteins and their annotated locations for NP_080898.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (a).
      Source sequence(s)
      AC160757
      Consensus CDS
      CCDS38422.2
      UniProtKB/Swiss-Prot
      Q3TQS7, Q562E0, Q8C0I3, Q8C1A9
      Related
      ENSMUSP00000124430.2, ENSMUST00000159774.7
      Conserved Domains (1) summary
      pfam09752
      Location:16 → 457
      DUF2048; Abhydrolase domain containing 18

    RNA

    1. NR_165084.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC160757, BC051081
      Related
      ENSMUST00000204496.3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      40825532..40892573
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017319591.2 → XP_017175080.1  protein ABHD18 isoform X1

      UniProtKB/Swiss-Prot
      Q3TQS7, Q562E0, Q8C0I3, Q8C1A9
      Conserved Domains (1) summary
      pfam09752
      Location:16 → 457
      DUF2048; Abhydrolase domain containing 18

    2. XM_030252629.2 → XP_030108489.1  protein ABHD18 isoform X3

      UniProtKB/TrEMBL
      B7ZNF5
      Conserved Domains (1) summary
      cl21494
      Location:1 → 288
      Abhydrolase; alpha/beta hydrolases

    3. XM_017319592.3 → XP_017175081.1  protein ABHD18 isoform X3

      UniProtKB/TrEMBL
      B7ZNF5
      Conserved Domains (1) summary
      cl21494
      Location:1 → 288
      Abhydrolase; alpha/beta hydrolases

    4. XM_036163124.1 → XP_036019017.1  protein ABHD18 isoform X3

      UniProtKB/TrEMBL
      B7ZNF5
      Conserved Domains (1) summary
      cl21494
      Location:1 → 288
      Abhydrolase; alpha/beta hydrolases

    5. XM_006500779.3 → XP_006500842.1  protein ABHD18 isoform X2

      See identical proteins and their annotated locations for XP_006500842.1

      UniProtKB/TrEMBL
      B7ZNF5
      Conserved Domains (1) summary
      pfam09752
      Location:1 → 381
      DUF2048; Abhydrolase domain containing 18

    RNA

    1. XR_001783694.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8C1A9.1 GenPept UniProtKB/Swiss-Prot:Q8C1A9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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