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    Msantd3 Myb/SANT-like DNA-binding domain containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 66665, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Msantd3provided by MGI
    Official Full Name
    Myb/SANT-like DNA-binding domain containing 3provided by MGI
    Primary source
    MGI:MGI:1913915
    See related
    Ensembl:ENSMUSG00000039693 AllianceGenome:MGI:1913915
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mysantd3; 2410046L14Rik; 2810429P03Rik; 5730528L13Rik
    Summary
    Orthologous to human MSANTD3 (Myb/SANT DNA binding domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E11.5 (RPKM 8.9), CNS E14 (RPKM 7.5) and 16 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Msantd3 in Genome Data Viewer
    Location:
    4 B1; 4 26.13 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (48539532..48565892)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (48539854..48565892)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene inversin Neighboring gene heterogeneous nuclear ribonucleoprotein F pseudogene Neighboring gene testis expressed gene 10 Neighboring gene STARR-positive B cell enhancer ABC_E6178 Neighboring gene STARR-seq mESC enhancer starr_10161 Neighboring gene STARR-seq mESC enhancer starr_10162 Neighboring gene STARR-seq mESC enhancer starr_10163 Neighboring gene STARR-seq mESC enhancer starr_10164 Neighboring gene STARR-seq mESC enhancer starr_10167 Neighboring gene transmembrane protein with EGF-like and two follistatin-like domains 1 Neighboring gene caveolae associated 4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Enhanced serotonin response in the hippocampus of Galphaz protein knock-out mice. Oleskevich S, et al. Neuroreport, 2005 Jun 21. PMID 15931062
    2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    3. BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. Stryke D, et al. Nucleic Acids Res, 2003 Jan 1. PMID 12520002, Free PMC Article
    4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    5. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    myb/SANT-like DNA-binding domain-containing protein 3
    Names
    UPF0439 protein C9orf30 homolog

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145924.1 → NP_001139396.1  myb/SANT-like DNA-binding domain-containing protein 3

      See identical proteins and their annotated locations for NP_001139396.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. All three transcripts encode the same protein.
      Source sequence(s)
      AK011381, AK017795, BC052696
      Consensus CDS
      CCDS18167.1
      UniProtKB/Swiss-Prot
      Q9CR78, Q9CYY5
      Related
      ENSMUSP00000065785.3, ENSMUST00000064807.9
      Conserved Domains (1) summary
      pfam13873
      Location:10 → 87
      Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain

    2. NM_001145925.1 → NP_001139397.1  myb/SANT-like DNA-binding domain-containing protein 3

      See identical proteins and their annotated locations for NP_001139397.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR compared to variant 1. All three transcripts encode the same protein.
      Source sequence(s)
      AK075956, BC052696
      Consensus CDS
      CCDS18167.1
      UniProtKB/Swiss-Prot
      Q9CR78, Q9CYY5
      Related
      ENSMUSP00000056551.2, ENSMUST00000061135.8
      Conserved Domains (1) summary
      pfam13873
      Location:10 → 87
      Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain

    3. NM_028137.3 → NP_082413.2  myb/SANT-like DNA-binding domain-containing protein 3

      See identical proteins and their annotated locations for NP_082413.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. All three transcripts encode the same protein.
      Source sequence(s)
      BC052696
      Consensus CDS
      CCDS18167.1
      UniProtKB/Swiss-Prot
      Q9CR78, Q9CYY5
      Related
      ENSMUSP00000103332.2, ENSMUST00000107704.2
      Conserved Domains (1) summary
      pfam13873
      Location:10 → 87
      Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      48539532..48565892
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006538188.5 → XP_006538251.1  myb/SANT-like DNA-binding domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006538251.1

      UniProtKB/Swiss-Prot
      Q9CR78, Q9CYY5
      Conserved Domains (1) summary
      pfam13873
      Location:10 → 87
      Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain

    2. XM_036164344.1 → XP_036020237.1  myb/SANT-like DNA-binding domain-containing protein 3 isoform X1

      UniProtKB/Swiss-Prot
      Q9CR78, Q9CYY5
      Conserved Domains (1) summary
      pfam13873
      Location:10 → 87
      Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain

    3. XM_011250086.4 → XP_011248388.1  myb/SANT-like DNA-binding domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_011248388.1

      UniProtKB/Swiss-Prot
      Q9CR78, Q9CYY5
      Conserved Domains (1) summary
      pfam13873
      Location:10 → 87
      Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain

    4. XM_006538187.4 → XP_006538250.1  myb/SANT-like DNA-binding domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006538250.1

      UniProtKB/Swiss-Prot
      Q9CR78, Q9CYY5
      Conserved Domains (1) summary
      pfam13873
      Location:10 → 87
      Myb_DNA-bind_5; Myb/SANT-like DNA-binding domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9CR78.1 GenPept UniProtKB/Swiss-Prot:Q9CR78

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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