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    Troap trophinin associated protein [ Mus musculus (house mouse) ]

    Gene ID: 78733, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Troapprovided by MGI
    Official Full Name
    trophinin associated proteinprovided by MGI
    Primary source
    MGI:MGI:1925983
    See related
    Ensembl:ENSMUSG00000032783 AllianceGenome:MGI:1925983
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    tastin; E130301L11Rik
    Summary
    Predicted to act upstream of or within cell adhesion. Predicted to be located in cytoplasm. Orthologous to human TROAP (trophinin associated protein). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in limb E14.5 (RPKM 9.0), CNS E11.5 (RPKM 8.9) and 20 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    15 F1; 15 55.8 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (98972854..98981290)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (99074973..99083409)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene peripherin Neighboring gene predicted gene, 34284 Neighboring gene STARR-positive B cell enhancer ABC_E947 Neighboring gene microRNA 6960 Neighboring gene complement component 1, q subcomponent-like 4 Neighboring gene DnaJ heat shock protein family (Hsp40) member C22

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. The interactome of CLUH reveals its association to SPAG5 and its co-translational proximity to mitochondrial proteins. Hémono M, et al. BMC Biol, 2022 Jan 10. PMID 35012549, Free PMC Article
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    4. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    acts_upstream_of_or_within cell adhesion IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tastin
    Names
    trophinin-assisting protein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001162506.1 → NP_001155978.1  tastin

      See identical proteins and their annotated locations for NP_001155978.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      BC100405, BC145227
      Consensus CDS
      CCDS57008.1
      UniProtKB/Swiss-Prot
      B7ZNG4, Q497S4, Q8BWP3
      Related
      ENSMUSP00000155404.2, ENSMUST00000230054.2
      Conserved Domains (1) summary
      PHA03247
      Location:473 → 642
      PHA03247; large tegument protein UL36; Provisional

    2. NM_030159.1 → NP_084435.1  tastin

      See identical proteins and their annotated locations for NP_084435.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      BC080746, BC100405, BC145227
      Consensus CDS
      CCDS57008.1
      UniProtKB/Swiss-Prot
      B7ZNG4, Q497S4, Q8BWP3
      Related
      ENSMUSP00000035389.7, ENSMUST00000039665.8
      Conserved Domains (1) summary
      PHA03247
      Location:473 → 642
      PHA03247; large tegument protein UL36; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      98972854..98981290
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030248822.1 → XP_030104682.1  tastin isoform X2

      Conserved Domains (1) summary
      PHA03247
      Location:166 → 335
      PHA03247; large tegument protein UL36; Provisional

    2. XM_036159638.1 → XP_036015531.1  tastin isoform X1

      Conserved Domains (1) summary
      PHA03247
      Location:227 → 396
      PHA03247; large tegument protein UL36; Provisional
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B7ZNG4.1 GenPept UniProtKB/Swiss-Prot:B7ZNG4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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