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    Aspg asparaginase [ Mus musculus (house mouse) ]

    Gene ID: 104816, updated on 6-May-2021

    Summary

    Official Symbol
    Aspgprovided by MGI
    Official Full Name
    asparaginaseprovided by MGI
    Primary source
    MGI:MGI:2144822
    See related
    Ensembl:ENSMUSG00000037686
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm690; AI429460; A530050D06Rik
    Expression
    Biased expression in liver adult (RPKM 84.5), colon adult (RPKM 14.5) and 7 other tissues See more
    Orthologs
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    Genomic context

    See Aspg in Genome Data Viewer
    Location:
    12; 12 F1
    Exon count:
    17
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (112073117..112094007)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (112106683..112127573)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (113344894..113365784)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene tudor domain containing 9 Neighboring gene retinal degeneration 3-like Neighboring gene predicted gene, 46381 Neighboring gene microRNA 3073a Neighboring gene microRNA 3073b Neighboring gene microRNA 203b Neighboring gene microRNA 203 Neighboring gene kinesin family member 26A

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 1-alkyl-2-acetylglycerophosphocholine esterase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables acyltransferase activity, transferring groups other than amino-acyl groups ISO
    Inferred from Sequence Orthology
    more info
     
    enables asparaginase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables asparaginase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables lysophospholipase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables phosphatidyl phospholipase B activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within asparagine metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular amino acid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within phospholipid metabolic process ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    60 kDa lysophospholipase
    Names
    60 kDa lysophospholipase [Includes: L-asparaginase
    asparaginase homolog
    lysophospholipase-transacylase
    NP_001074638.1
    XP_006515408.1
    XP_006515409.1
    XP_006515410.1
    XP_006515411.1
    XP_006515412.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081169.1NP_001074638.1  60 kDa lysophospholipase

      See identical proteins and their annotated locations for NP_001074638.1

      Status: PROVISIONAL

      Source sequence(s)
      AC112520
      Consensus CDS
      CCDS36567.1
      UniProtKB/Swiss-Prot
      A0JNU3
      Related
      ENSMUSP00000078369.5, ENSMUST00000079400.6
      Conserved Domains (3) summary
      PLN03192
      Location:373550
      PLN03192; Voltage-dependent potassium channel; Provisional
      sd00045
      Location:430461
      ANK; ANK repeat [structural motif]
      cl00216
      Location:9361
      L-asparaginase_like; Bacterial L-asparaginases and related enzymes

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      112073117..112094007
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006515345.5XP_006515408.1  60 kDa lysophospholipase isoform X1

      Conserved Domains (3) summary
      PLN03192
      Location:330507
      PLN03192; Voltage-dependent potassium channel; Provisional
      sd00045
      Location:387418
      ANK; ANK repeat [structural motif]
      cl00216
      Location:31318
      L-asparaginase_like; Bacterial L-asparaginases and related enzymes
    2. XM_006515346.1XP_006515409.1  60 kDa lysophospholipase isoform X2

      See identical proteins and their annotated locations for XP_006515409.1

      Conserved Domains (3) summary
      PLN03192
      Location:255432
      PLN03192; Voltage-dependent potassium channel; Provisional
      sd00045
      Location:312343
      ANK; ANK repeat [structural motif]
      cl00216
      Location:1243
      L-asparaginase_like; Bacterial L-asparaginases and related enzymes
    3. XM_006515349.1XP_006515412.1  60 kDa lysophospholipase isoform X3

      Conserved Domains (3) summary
      PLN03192
      Location:211388
      PLN03192; Voltage-dependent potassium channel; Provisional
      sd00045
      Location:268299
      ANK; ANK repeat [structural motif]
      cl00216
      Location:2199
      L-asparaginase_like; Bacterial L-asparaginases and related enzymes
    4. XM_006515348.1XP_006515411.1  60 kDa lysophospholipase isoform X2

      See identical proteins and their annotated locations for XP_006515411.1

      Conserved Domains (3) summary
      PLN03192
      Location:255432
      PLN03192; Voltage-dependent potassium channel; Provisional
      sd00045
      Location:312343
      ANK; ANK repeat [structural motif]
      cl00216
      Location:1243
      L-asparaginase_like; Bacterial L-asparaginases and related enzymes
    5. XM_006515347.5XP_006515410.1  60 kDa lysophospholipase isoform X2

      See identical proteins and their annotated locations for XP_006515410.1

      Conserved Domains (3) summary
      PLN03192
      Location:255432
      PLN03192; Voltage-dependent potassium channel; Provisional
      sd00045
      Location:312343
      ANK; ANK repeat [structural motif]
      cl00216
      Location:1243
      L-asparaginase_like; Bacterial L-asparaginases and related enzymes
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