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    Rbm45 RNA binding motif protein 45 [ Mus musculus (house mouse) ]

    Gene ID: 241490, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rbm45provided by MGI
    Official Full Name
    RNA binding motif protein 45provided by MGI
    Primary source
    MGI:MGI:2387367
    See related
    Ensembl:ENSMUSG00000042369
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Drb; Drb1; Drbp1; G430095G15Rik
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 13.8), CNS E14 (RPKM 13.6) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Rbm45 in Genome Data Viewer
    Location:
    2; 2 C3
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (76200304..76214112)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (76369959..76383768)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (76208041..76221825)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 11A Neighboring gene predicted gene, 52518 Neighboring gene cytochrome c, testis Neighboring gene oxysterol binding protein-like 6 Neighboring gene protein kinase, interferon inducible double stranded RNA dependent activator

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA binding ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within nervous system development IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ribonucleoprotein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 

    General protein information

    Preferred Names
    RNA-binding protein 45
    Names
    RB-1
    developmentally regulated RNA binding protein 1
    dopamine receptor binding 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153405.2NP_700454.1  RNA-binding protein 45

      See identical proteins and their annotated locations for NP_700454.1

      Status: VALIDATED

      Source sequence(s)
      AK080420, AK140861, BB832413, CB597326
      Consensus CDS
      CCDS16157.1
      UniProtKB/Swiss-Prot
      Q8BHN5
      UniProtKB/TrEMBL
      Q3US38
      Related
      ENSMUSP00000040420.5, ENSMUST00000046389.5
      Conserved Domains (4) summary
      cd12366
      Location:23104
      RRM1_RBM45; RNA recognition motif 1 in RNA-binding protein 45 (RBM45) and similar proteins
      cd12367
      Location:120193
      RRM2_RBM45; RNA recognition motif 2 in RNA-binding protein 45 (RBM45) and similar proteins
      cd12368
      Location:248320
      RRM3_RBM45; RNA recognition motif 3 in RNA-binding protein 45 (RBM45) and similar proteins
      cd12369
      Location:393460
      RRM4_RBM45; RNA recognition motif 4 in RNA-binding protein 45 (RBM45) and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      76200304..76214112
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_003952822.2 RNA Sequence

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_178090.2: Suppressed sequence

      Description
      NM_178090.2: This RefSeq was permanently suppressed because it contains a single nucleotide frameshift mutation that truncates the C-terminus of the protein and makes this transcript a candidate for nonsense-mediated mRNA decay (
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