Serpina4-ps1 serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Serpina4-ps1provided by MGI
Official Full Name: serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1provided by MGI
Primary source: MGI:MGI:2448363
See related: AllianceGenome:MGI:2448363
Gene type: pseudo
RefSeq status: INFERRED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Klst; KALps
Summary: Is expressed in liver. [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward liver E18 (RPKM 43.9) See more
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Genomic context

Location:: 12 E; 12 53.23 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	12	NC_000078.7 (104044218..104053179)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	12	NC_000078.6 (104077959..104086920)

Chromosome 12 - NC_000078.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Endogenous kallistatin through novel mechanisms protects against endothelial senescence by modulating Let-7g-mediated miR-34a-SIRT1-eNOS pathway.
Title: Kallistatin attenuates endothelial senescence by modulating Let-7g-mediated miR-34a-SIRT1-eNOS pathway.
our results showed that the lymphatic vessel density (LVD) was reduced in lung and stomach sections from kallistatin-overexpressing transgenic mice
Title: Kallistatin exerts anti-lymphangiogenic effects by inhibiting lymphatic endothelial cell proliferation, migration and tube formation.
KBP reduces expression of VEGF and HIF-1alpha nuclear translocation
Title: Kallikrein-binding protein suppresses growth of hepatocellular carcinoma by anti-angiogenic activity.

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General gene information

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Markers

30.MMHAP12FLB6.seq (e-PCR)
- UniSTS:123889

Other Names

kallistatin related protein
serine (or cysteine) proteinase inhibitor, clade A, member 4, pseudogene 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

NR_002861.2 RNA Sequence

Status: INFERRED

Source sequence(s)

AC114552, AC142112

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000078.7 Reference GRCm39 C57BL/6J

Range

104044218..104053179

Download

GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_177315.1: Suppressed sequence

Description

NM_177315.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.