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    Rdh7 retinol dehydrogenase 7 [ Mus musculus (house mouse) ]

    Gene ID: 54150, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rdh7provided by MGI
    Official Full Name
    retinol dehydrogenase 7provided by MGI
    Primary source
    MGI:MGI:1860517
    See related
    Ensembl:ENSMUSG00000040134
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    CRA; CRAD2; AI194929
    Expression
    Biased expression in liver adult (RPKM 592.0) and liver E18 (RPKM 146.7) See more
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    Genomic context

    See Rdh7 in Genome Data Viewer
    Location:
    10; 10 D3
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (127719896..127725116, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (127884027..127889247, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (127321083..127326303, complement)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene retinol dehydrogenase 19 Neighboring gene RDH16 family member 2 Neighboring gene predicted gene, 31091 Neighboring gene 4short chain dehydrogenase/reductase family 9C, member 7 Neighboring gene predicted gene, 40804

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables NAD-retinol dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables androstan-3-alpha,17-beta-diol dehydrogenase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables androsterone dehydrogenase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables catalytic activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in steroid metabolic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    retinol dehydrogenase 7
    Names
    CRAD-2
    cis-retinol/3alpha-hydroxysterol short-chain dehydrogenase isozyme 2
    cis-retinol/androgen dehydrogenase type 2
    NP_001144221.1
    NP_059501.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001150749.1NP_001144221.1  retinol dehydrogenase 7 precursor

      See identical proteins and their annotated locations for NP_001144221.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AB015165, AI255893, CB951082, CJ097101
      Consensus CDS
      CCDS24255.1
      UniProtKB/Swiss-Prot
      O88451
      Related
      ENSMUSP00000039252.5, ENSMUST00000047199.5
      Conserved Domains (2) summary
      cd09805
      Location:30305
      type2_17beta_HSD-like_SDR_c; human 17beta-hydroxysteroid dehydrogenase type 2 (type 2 17beta-HSD)-like, classical (c) SDRs
      pfam00106
      Location:30217
      adh_short; short chain dehydrogenase
    2. NM_017473.4NP_059501.1  retinol dehydrogenase 7 precursor

      See identical proteins and their annotated locations for NP_059501.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses a different segment for its 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein.
      Source sequence(s)
      AA260496, AC131690, AF056194
      Consensus CDS
      CCDS24255.1
      UniProtKB/Swiss-Prot
      O88451
      Conserved Domains (2) summary
      cd09805
      Location:30305
      type2_17beta_HSD-like_SDR_c; human 17beta-hydroxysteroid dehydrogenase type 2 (type 2 17beta-HSD)-like, classical (c) SDRs
      pfam00106
      Location:30217
      adh_short; short chain dehydrogenase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      127719896..127725116 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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