Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Nars asparaginyl-tRNA synthetase [ Mus musculus (house mouse) ]

    Gene ID: 70223, updated on 8-Jul-2021

    Summary

    Official Symbol
    Narsprovided by MGI
    Official Full Name
    asparaginyl-tRNA synthetaseprovided by MGI
    Primary source
    MGI:MGI:1917473
    See related
    Ensembl:ENSMUSG00000024587
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ASNRS; NARS1; C78150; AA960128; 3010001M15Rik
    Expression
    Ubiquitous expression in liver E14 (RPKM 51.7), placenta adult (RPKM 44.5) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Nars in Genome Data Viewer
    Location:
    18; 18 E1
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (64632726..64649586, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (64499655..64516515, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (64659301..64676211, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene S-adenosylmethionine decarboxylase, pseudogene 3 Neighboring gene ferrochelatase Neighboring gene ATPase, class I, type 8B, member 1 Neighboring gene predicted gene 6978 Neighboring gene predicted gene, 23016

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables CCR3 chemokine receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables aminoacyl-tRNA ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables asparagine-tRNA ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables ligase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein dimerization activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in asparaginyl-tRNA aminoacylation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cerebral cortex development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in tRNA aminoacylation for protein translation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion HDA PubMed 

    General protein information

    Preferred Names
    asparagine--tRNA ligase, cytoplasmic
    Names
    asparaginyl-tRNA synthetase 1
    asparaginyl-tRNA synthetase, cytoplasmic
    NP_001136422.2
    NP_001363950.1
    NP_001363951.1
    NP_001363952.1
    NP_081626.3

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001142950.2NP_001136422.2  asparagine--tRNA ligase, cytoplasmic isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC102268
      Consensus CDS
      CCDS50308.1
      Related
      ENSMUSP00000157402.2, ENSMUST00000237400.2
      Conserved Domains (1) summary
      COG0017
      Location:125548
      AsnS; Aspartyl/asparaginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
    2. NM_001377021.1NP_001363950.1  asparagine--tRNA ligase, cytoplasmic isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC102268
      Conserved Domains (1) summary
      COG0017
      Location:126549
      AsnS; Aspartyl/asparaginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
    3. NM_001377022.1NP_001363951.1  asparagine--tRNA ligase, cytoplasmic isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC102268
      Conserved Domains (1) summary
      COG0017
      Location:125546
      AsnS; Aspartyl/asparaginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
    4. NM_001377023.1NP_001363952.1  asparagine--tRNA ligase, cytoplasmic isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC102268
      Related
      ENSMUSP00000158278.2, ENSMUST00000237351.2
      Conserved Domains (1) summary
      COG0017
      Location:95518
      AsnS; Aspartyl/asparaginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]
    5. NM_027350.4NP_081626.3  asparagine--tRNA ligase, cytoplasmic isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC102268
      Consensus CDS
      CCDS89261.1
      Related
      ENSMUSP00000025483.11, ENSMUST00000025483.11
      Conserved Domains (1) summary
      COG0017
      Location:124547
      AsnS; Aspartyl/asparaginyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      64632726..64649586 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center