Trim75 tripartite motif-containing 75 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Trim75provided by MGI
Official Full Name: tripartite motif-containing 75provided by MGI
Primary source: MGI:MGI:2685640
See related: Ensembl:ENSMUSG00000071089 AllianceGenome:MGI:2685640
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm794
Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response; protein ubiquitination; and regulation of gene expression. Predicted to be active in cytoplasm. Orthologous to human TRIM75 (tripartite motif containing 75). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in ovary adult (RPKM 1.4) and kidney adult (RPKM 0.1) See more
Orthologs: human all
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Genomic context

Location:: 8 B3.1; 8 32.48 cM

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	8	NC_000074.7 (65434303..65440296, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	8	NC_000074.6 (64981651..64987644, complement)

Chromosome 8 - NC_000074.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables ubiquitin protein ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in female meiosis I	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in protein ubiquitination	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: tripartite motif-containing protein 75

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001033429.2 → NP_001028601.1 tripartite motif-containing protein 75

See identical proteins and their annotated locations for NP_001028601.1

Status: PROVISIONAL

Source sequence(s)

AK136018

Consensus CDS

CCDS22330.1

UniProtKB/Swiss-Prot

Q3UWZ0

UniProtKB/TrEMBL

B2RTB3

Related

ENSMUSP00000092932.2, ENSMUST00000095295.3

Conserved Domains (3) summary

smart00336
Location:90 → 131

BBOX; B-Box-type zinc finger

pfam15227
Location:16 → 56

zf-C3HC4_4; zinc finger of C3HC4-type, RING

cd15829
Location:276 → 460

SPRY_PRY_TRIM75; PRY/SPRY domain of tripartite motif-binding protein 75 (TRIM75)