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    Ptgdr2 prostaglandin D2 receptor 2 [ Mus musculus (house mouse) ]

    Gene ID: 14764, updated on 14-Sep-2021

    Summary

    Official Symbol
    Ptgdr2provided by MGI
    Official Full Name
    prostaglandin D2 receptor 2provided by MGI
    Primary source
    MGI:MGI:1330275
    See related
    Ensembl:ENSMUSG00000034117
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gpr; Crth; Crth2; Gpr44; Grp45
    Expression
    Broad expression in ovary adult (RPKM 2.6), subcutaneous fat pad adult (RPKM 1.9) and 15 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Ptgdr2 in Genome Data Viewer
    Location:
    19; 19 A
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (10901883..10919875)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (10924519..10942511)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (11011650..11017001)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene pre-mRNA processing factor 19 Neighboring gene zona pellucida glycoprotein 1 Neighboring gene coiled-coil domain containing 86 Neighboring gene membrane-spanning 4-domains, subfamily A, member 10 Neighboring gene membrane-spanning 4-domains, subfamily A, member 15

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    General gene information

    Homology

    Clone Names

    • MGC130436

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables G protein-coupled receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables G protein-coupled receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables G protein-coupled receptor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    enables neuropeptide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables peptide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables prostaglandin D receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables prostaglandin D receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables prostaglandin D receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables prostaglandin F receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables prostaglandin J receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in integral component of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    prostaglandin D2 receptor 2
    Names
    G-protein coupled receptor 44
    PGD2 receptor
    chemoattractant receptor-homologous molecule expressed on TH2 cells
    prostaglandin D2 receptor CRTH2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009962.3NP_034092.1  prostaglandin D2 receptor 2

      See identical proteins and their annotated locations for NP_034092.1

      Status: VALIDATED

      Source sequence(s)
      AC132402, AC148991, AK041947
      Consensus CDS
      CCDS29592.1
      UniProtKB/Swiss-Prot
      Q9Z2J6
      Related
      ENSMUSP00000036159.4, ENSMUST00000037261.4
      Conserved Domains (2) summary
      cd14964
      Location:3458
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:32314
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      10901883..10919875
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011247148.4XP_011245450.1  prostaglandin D2 receptor 2 isoform X1

      See identical proteins and their annotated locations for XP_011245450.1

      UniProtKB/Swiss-Prot
      Q9Z2J6
      Conserved Domains (2) summary
      cd14964
      Location:3458
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:32314
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    2. XM_006526695.5XP_006526758.1  prostaglandin D2 receptor 2 isoform X1

      See identical proteins and their annotated locations for XP_006526758.1

      UniProtKB/Swiss-Prot
      Q9Z2J6
      Conserved Domains (2) summary
      cd14964
      Location:3458
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:32314
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
    3. XM_006526696.5XP_006526759.1  prostaglandin D2 receptor 2 isoform X1

      See identical proteins and their annotated locations for XP_006526759.1

      UniProtKB/Swiss-Prot
      Q9Z2J6
      Conserved Domains (2) summary
      cd14964
      Location:3458
      7tm_GPCRs; TM helix 1 [structural motif]
      cl28897
      Location:32314
      7tm_GPCRs; seven-transmembrane G protein-coupled receptor superfamily
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