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    Cd3d CD3 antigen, delta polypeptide [ Mus musculus (house mouse) ]

    Gene ID: 12500, updated on 23-Jun-2021

    Summary

    Official Symbol
    Cd3dprovided by MGI
    Official Full Name
    CD3 antigen, delta polypeptideprovided by MGI
    Primary source
    MGI:MGI:88331
    See related
    Ensembl:ENSMUSG00000032094
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    T3d
    Expression
    Biased expression in thymus adult (RPKM 78.5), spleen adult (RPKM 9.8) and 1 other tissue See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Cd3d in Genome Data Viewer
    Location:
    9 A5.2; 9 24.84 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (44893067..44898350)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (44981769..44987052)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 9 NC_000075.5 (44789869..44795135)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene ubiquitination factor E4A Neighboring gene phosphatidylinositol glycan anchor biosynthesis, class A pseudogene Neighboring gene CD3 antigen, gamma polypeptide Neighboring gene CD3 antigen, epsilon polypeptide Neighboring gene myelin protein zero-like 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transmembrane signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in T cell activation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within adaptive immune response IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cell surface receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive thymic T cell selection IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in positive thymic T cell selection IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein-containing complex assembly NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of T cell receptor complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of T cell receptor complex NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of alpha-beta T cell receptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of alpha-beta T cell receptor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of alpha-beta T cell receptor complex ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    T-cell surface glycoprotein CD3 delta chain
    Names
    T-cell receptor T3 delta chain

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_013487.3NP_038515.3  T-cell surface glycoprotein CD3 delta chain precursor

      See identical proteins and their annotated locations for NP_038515.3

      Status: VALIDATED

      Source sequence(s)
      AK042172, BB237678, BC062807, BY576367
      Consensus CDS
      CCDS23124.1
      UniProtKB/Swiss-Prot
      P04235
      UniProtKB/TrEMBL
      Q3U4T1, Q3V3B4, Q6P5P1
      Related
      ENSMUSP00000034602.8, ENSMUST00000034602.9
      Conserved Domains (2) summary
      pfam02189
      Location:146165
      ITAM; Immunoreceptor tyrosine-based activation motif
      pfam16680
      Location:3195
      Ig_4; T-cell surface glycoprotein CD3 delta chain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      44893067..44898350
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006509965.1XP_006510028.1  T-cell surface glycoprotein CD3 delta chain isoform X1

      Conserved Domains (2) summary
      pfam02189
      Location:201220
      ITAM; Immunoreceptor tyrosine-based activation motif
      pfam16680
      Location:85158
      Ig_4; T-cell surface glycoprotein CD3 delta chain
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