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    Tmem51 transmembrane protein 51 [ Mus musculus (house mouse) ]

    Gene ID: 214359, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Tmem51provided by MGI
    Official Full Name
    transmembrane protein 51provided by MGI
    Primary source
    MGI:MGI:2384874
    See related
    Ensembl:ENSMUSG00000040616 AllianceGenome:MGI:2384874
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human TMEM51 (transmembrane protein 51). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in genital fat pad adult (RPKM 26.9), stomach adult (RPKM 26.2) and 24 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    4 D3; 4 75.17 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (141758301..141811985, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (142030990..142084928, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930455G09 gene Neighboring gene forkhead-associated phosphopeptide binding domain 1 Neighboring gene STARR-positive B cell enhancer ABC_E10274 Neighboring gene forkhead-associated phosphopeptide binding domain 1, opposite strand 1 Neighboring gene STARR-seq mESC enhancer starr_11942 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:141636026-141636227 Neighboring gene Tmem51 opposite strand 1 Neighboring gene STARR-seq mESC enhancer starr_11946 Neighboring gene STARR-seq mESC enhancer starr_11949 Neighboring gene STARR-seq mESC enhancer starr_11950 Neighboring gene predicted gene, 35581 Neighboring gene kazrin, periplakin interacting protein Neighboring gene predicted gene, 35531

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs. Pan J, et al. Am J Reprod Immunol, 2015 Sep. PMID 26073538
    2. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article
    3. The Vertebrate Genome Annotation browser 10 years on. Harrow JL, et al. Nucleic Acids Res, 2014 Jan. PMID 24316575, Free PMC Article
    4. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    5. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • FLJ10199

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transmembrane protein 51

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001419368.1 → NP_001406297.1  transmembrane protein 51

      Status: VALIDATED

      Source sequence(s)
      AL663037
      UniProtKB/Swiss-Prot
      Q3TPZ3, Q99LG1

    2. NM_001419370.1 → NP_001406299.1  transmembrane protein 51

      Status: VALIDATED

      Source sequence(s)
      AL663037
      UniProtKB/Swiss-Prot
      Q3TPZ3, Q99LG1

    3. NM_001419371.1 → NP_001406300.1  transmembrane protein 51

      Status: VALIDATED

      Source sequence(s)
      AL663037
      UniProtKB/Swiss-Prot
      Q3TPZ3, Q99LG1

    4. NM_001419372.1 → NP_001406301.1  transmembrane protein 51

      Status: VALIDATED

      Source sequence(s)
      AL663037
      UniProtKB/Swiss-Prot
      Q3TPZ3, Q99LG1

    5. NM_001419374.1 → NP_001406303.1  transmembrane protein 51

      Status: VALIDATED

      Source sequence(s)
      AL663037
      UniProtKB/Swiss-Prot
      Q3TPZ3, Q99LG1

    6. NM_145402.4 → NP_663377.1  transmembrane protein 51

      See identical proteins and their annotated locations for NP_663377.1

      Status: VALIDATED

      Source sequence(s)
      AL663037
      Consensus CDS
      CCDS18886.1
      UniProtKB/Swiss-Prot
      Q3TPZ3, Q99LG1
      Related
      ENSMUSP00000042919.4, ENSMUST00000036572.4
      Conserved Domains (1) summary
      pfam15345
      Location:7 → 236
      TMEM51; Transmembrane protein 51

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      141758301..141811985 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011250227.2 → XP_011248529.1  transmembrane protein 51 isoform X1

      See identical proteins and their annotated locations for XP_011248529.1

      UniProtKB/Swiss-Prot
      Q3TPZ3, Q99LG1
      Conserved Domains (1) summary
      pfam15345
      Location:7 → 236
      TMEM51; Transmembrane protein 51

    2. XM_006538715.5 → XP_006538778.1  transmembrane protein 51 isoform X1

      See identical proteins and their annotated locations for XP_006538778.1

      UniProtKB/Swiss-Prot
      Q3TPZ3, Q99LG1
      Conserved Domains (1) summary
      pfam15345
      Location:7 → 236
      TMEM51; Transmembrane protein 51
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q99LG1.1 GenPept UniProtKB/Swiss-Prot:Q99LG1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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