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    Rnf125 ring finger protein 125 [ Mus musculus (house mouse) ]

    Gene ID: 67664, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rnf125provided by MGI
    Official Full Name
    ring finger protein 125provided by MGI
    Primary source
    MGI:MGI:1914914
    See related
    Ensembl:ENSMUSG00000033107
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C730049O14; 4930553F04Rik; C730049O14Rik
    Expression
    Broad expression in liver adult (RPKM 19.3), testis adult (RPKM 9.0) and 18 other tissues See more
    Orthologs
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    Genomic context

    See Rnf125 in Genome Data Viewer
    Location:
    18; 18 A2
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (21077672..21120416)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (20944615..20987359)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (21103126..21142349)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6 Neighboring gene predicted gene, 31437 Neighboring gene trafficking protein particle complex 8 Neighboring gene ring finger protein 138 Neighboring gene ribosomal protein L27A pseudogene Neighboring gene meprin 1 beta

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables p53 binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin conjugating enzyme binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ubiquitin protein ligase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin-protein transferase activity EXP
    Inferred from Experiment
    more info
    PubMed 
    enables zinc ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of VCP-NPL4-UFD1 AAA ATPase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of VCP-NPL4-UFD1 AAA ATPase complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    E3 ubiquitin-protein ligase RNF125
    NP_001351902.1
    NP_080577.1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001364973.1NP_001351902.1  E3 ubiquitin-protein ligase RNF125 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC138611, AK016103, AK050462, BF148133, BY099954
      Consensus CDS
      CCDS89199.1
      Related
      ENSMUSP00000157304.2, ENSMUST00000234316.2
      Conserved Domains (2) summary
      pfam05605
      Location:142174
      zf-Di19; Drought induced 19 protein (Di19), zinc-binding
      cl17238
      Location:3577
      RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain
    2. NM_026301.3NP_080577.1  E3 ubiquitin-protein ligase RNF125 isoform 1

      See identical proteins and their annotated locations for NP_080577.1

      Status: VALIDATED

      Source sequence(s)
      AC138611, AK050395, AK050462, BF148133
      Consensus CDS
      CCDS29088.1
      UniProtKB/Swiss-Prot
      Q9D9R0
      Related
      ENSMUSP00000058251.2, ENSMUST00000050004.3
      Conserved Domains (1) summary
      pfam05605
      Location:4981
      zf-Di19; Drought induced 19 protein (Di19), zinc-binding

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      21077672..21120416
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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