Semp2l2b SUMO/sentrin specific peptidase 2-like 2B [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Semp2l2bprovided by MGI
Official Full Name: SUMO/sentrin specific peptidase 2-like 2Bprovided by MGI
Primary source: MGI:MGI:2149738
See related: Ensembl:ENSMUSG00000069712 AllianceGenome:MGI:2149738
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 4930444G20Rik
Summary: Predicted to enable SUMO-specific endopeptidase activity. Predicted to be involved in protein destabilization; protein desumoylation; and regulation of protein ubiquitination. Predicted to be located in cytosol. Predicted to be part of nuclear pore. Predicted to be active in nucleus. Orthologous to human SENP2 (SUMO specific peptidase 2). [provided by Alliance of Genome Resources, Apr 2022]
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Genomic context

Location:: 10 A3; 10 9.83 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	10	NC_000076.7 (21942208..21943978, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	10	NC_000076.6 (22066309..22068079, complement)

Chromosome 10 - NC_000076.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables deSUMOylase activity	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in protein desumoylation	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: SUMO/sentrin specific peptidase-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_053264.2 → NP_444494.1 SUMO/sentrin specific peptidase-like

Status: VALIDATED

Source sequence(s)

AC153555, AK015380

Consensus CDS

CCDS48519.1

UniProtKB/TrEMBL

D3Z741, Q71RI2

Related

ENSMUSP00000097613.4, ENSMUST00000092672.6

Conserved Domains (1) summary

cl23802
Location:272 → 490

Peptidase_C48; Ulp1 protease family, C-terminal catalytic domain