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    Mup10 major urinary protein 10 [ Mus musculus (house mouse) ]

    Gene ID: 100039008, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Mup10provided by MGI
    Official Full Name
    major urinary protein 10provided by MGI
    Primary source
    MGI:MGI:1924164
    See related
    Ensembl:ENSMUSG00000078680 AllianceGenome:MGI:1924164
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mup8; 2610016E04Rik
    Summary
    Predicted to enable odorant binding activity. Predicted to be active in extracellular space. Is expressed in liver. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward liver adult (RPKM 2910.2) See more
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    Genomic context

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    Location:
    4 B3; 4 32.85 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (60534259..60538275, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (60578260..60582276, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene major urinary protein, pseudogene 6 Neighboring gene major urinary protein, pseudogene 24 Neighboring gene major urinary protein, pseudogene 5 Neighboring gene major urinary protein 11

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Complete 1H, 15N and 13C assignment of a recombinant mouse major urinary protein. Abbate F, et al. J Biomol NMR, 1999 Oct. PMID 10605093
    2. Solution structure of a recombinant mouse major urinary protein. Lücke C, et al. Eur J Biochem, 1999 Dec. PMID 10583419
    3. Expression of a lipocalin in Pichia pastoris: secretion, purification and binding activity of a recombinant mouse major urinary protein. Ferrari E, et al. FEBS Lett, 1997 Jan 13. PMID 9003809
    4. Zhx2 (zinc fingers and homeoboxes 2) regulates major urinary protein gene expression in the mouse liver. Jiang J, et al. J Biol Chem, 2017 Apr 21. PMID 28258223, Free PMC Article
    5. Species specificity in major urinary proteins by parallel evolution. Logan DW, et al. PLoS One, 2008 Sep 25. PMID 18815613, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables odorant binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in extracellular space ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    major urinary protein 10
    Names
    major urinary protein 8

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001122647.1 → NP_001116119.1  major urinary protein 10 precursor

      See identical proteins and their annotated locations for NP_001116119.1

      Status: VALIDATED

      Source sequence(s)
      AI118190, BX950196, CB948918
      Consensus CDS
      CCDS51189.1
      UniProtKB/Swiss-Prot
      P11589, Q99JF6
      UniProtKB/TrEMBL
      A2BIN1
      Related
      ENSMUSP00000095655.3, ENSMUST00000098047.3
      Conserved Domains (1) summary
      pfam00061
      Location:34 → 170
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      60534259..60538275 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006537481.2 → XP_006537544.1  major urinary protein 10 isoform X1

      Conserved Domains (1) summary
      cd19428
      Location:23 → 172
      lipocalin_MUP-like; major urinary proteins (MUPs) and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version

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