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    Ppp1r26 protein phosphatase 1, regulatory subunit 26 [ Mus musculus (house mouse) ]

    Gene ID: 241289, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Ppp1r26provided by MGI
    Official Full Name
    protein phosphatase 1, regulatory subunit 26provided by MGI
    Primary source
    MGI:MGI:2685193
    See related
    Ensembl:ENSMUSG00000035829 AllianceGenome:MGI:2685193
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm347; Kiaa0649; mKIAA0649
    Summary
    Predicted to enable protein phosphatase inhibitor activity. Predicted to be involved in negative regulation of phosphatase activity. Predicted to be located in nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and respiratory system. Orthologous to human PPP1R26 (protein phosphatase 1 regulatory subunit 26). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E18 (RPKM 5.2), whole brain E14.5 (RPKM 4.8) and 20 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    2 A3; 2 19.38 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (28336613..28345520)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (28446493..28455508)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_04018 Neighboring gene olfactomedin 1 Neighboring gene predicted gene 13373 Neighboring gene STARR-seq mESC enhancer starr_04019 Neighboring gene STARR-seq mESC enhancer starr_04020 Neighboring gene piercer of microtubule wall 1 Neighboring gene ribosomal protein SA, pseudogene 9 Neighboring gene mitochondrial ribosomal protein S2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Jun 30. PMID 15368895
    2. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC99945

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein phosphatase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    protein phosphatase 1 regulatory subunit 26

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005420.3 → NP_001005420.1  protein phosphatase 1 regulatory subunit 26

      See identical proteins and their annotated locations for NP_001005420.1

      Status: VALIDATED

      Source sequence(s)
      AL772249
      Consensus CDS
      CCDS15836.1
      UniProtKB/Swiss-Prot
      Q6A025, Q6NS64
      Conserved Domains (1) summary
      pfam15740
      Location:1 → 806
      PPP1R26_N; Protein phosphatase 1 regulatory subunit 26 N-terminus

    2. NM_001368159.2 → NP_001355088.1  protein phosphatase 1 regulatory subunit 26

      Status: VALIDATED

      Source sequence(s)
      AL772249
      Consensus CDS
      CCDS15836.1
      UniProtKB/Swiss-Prot
      Q6A025, Q6NS64
      Conserved Domains (1) summary
      pfam15740
      Location:1 → 806
      PPP1R26_N; Protein phosphatase 1 regulatory subunit 26 N-terminus

    3. NM_001411194.1 → NP_001398123.1  protein phosphatase 1 regulatory subunit 26

      Status: VALIDATED

      Source sequence(s)
      AL772249
      UniProtKB/Swiss-Prot
      Q6A025, Q6NS64

    4. NM_001411195.1 → NP_001398124.1  protein phosphatase 1 regulatory subunit 26

      Status: VALIDATED

      Source sequence(s)
      AL772249
      UniProtKB/Swiss-Prot
      Q6A025, Q6NS64

    5. NM_001411196.1 → NP_001398125.1  protein phosphatase 1 regulatory subunit 26

      Status: VALIDATED

      Source sequence(s)
      AL772249
      UniProtKB/Swiss-Prot
      Q6A025, Q6NS64

    6. NM_001411197.1 → NP_001398126.1  protein phosphatase 1 regulatory subunit 26

      Status: VALIDATED

      Source sequence(s)
      AL772249
      UniProtKB/Swiss-Prot
      Q6A025, Q6NS64

    7. NM_001411198.1 → NP_001398127.1  protein phosphatase 1 regulatory subunit 26

      Status: VALIDATED

      Source sequence(s)
      AL772249
      UniProtKB/Swiss-Prot
      Q6A025, Q6NS64

    8. NM_001411199.1 → NP_001398128.1  protein phosphatase 1 regulatory subunit 26

      Status: VALIDATED

      Source sequence(s)
      AL772249
      UniProtKB/Swiss-Prot
      Q6A025, Q6NS64
      Related
      ENSMUSP00000042173.8, ENSMUST00000040324.14

    9. NM_001411200.1 → NP_001398129.1  protein phosphatase 1 regulatory subunit 26

      Status: VALIDATED

      Source sequence(s)
      AL772249
      UniProtKB/Swiss-Prot
      Q6A025, Q6NS64

    10. NM_001411201.1 → NP_001398130.1  protein phosphatase 1 regulatory subunit 26

      Status: VALIDATED

      Source sequence(s)
      AL772249
      UniProtKB/Swiss-Prot
      Q6A025, Q6NS64

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      28336613..28345520
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6A025.2 GenPept UniProtKB/Swiss-Prot:Q6A025

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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