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    Bach2 BTB and CNC homology, basic leucine zipper transcription factor 2 [ Mus musculus (house mouse) ]

    Gene ID: 12014, updated on 21-Oct-2021

    Summary

    Official Symbol
    Bach2provided by MGI
    Official Full Name
    BTB and CNC homology, basic leucine zipper transcription factor 2provided by MGI
    Primary source
    MGI:MGI:894679
    See related
    Ensembl:ENSMUSG00000040270
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    E030004N02Rik
    Expression
    Broad expression in whole brain E14.5 (RPKM 5.3), CNS E14 (RPKM 5.0) and 24 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Bach2 in Genome Data Viewer
    Location:
    4; 4 A5
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (32238413..32586109)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (32238413..32586109)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 4 NC_000070.5 (32504410..32673083)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene nuclear encoded tRNA glycine 3 (anticodon CCC) Neighboring gene VISTA enhancer mm720 Neighboring gene VISTA enhancer mm510 Neighboring gene BTB and CNC homology 2, opposite strand Neighboring gene caspase 8 associated protein 2 Neighboring gene gap junction protein, alpha 10

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (8)  1 citation
    • Chemically induced (ENU) (3) 
    • Endonuclease-mediated (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    Clone Names

    • MGC117590

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    transcription regulator protein BACH2
    Names
    BTB and CNC homolog 2
    BTB and CNC homology 2
    Transcription regulator protein BACH2 (BTB and CNC homolog 2)

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001109661.1NP_001103131.1  transcription regulator protein BACH2

      See identical proteins and their annotated locations for NP_001103131.1

      Status: VALIDATED

      Source sequence(s)
      AL831746, BC131642, CX200493
      Consensus CDS
      CCDS51135.1
      UniProtKB/Swiss-Prot
      P97303
      Related
      ENSMUSP00000131592.2, ENSMUST00000171600.2
      Conserved Domains (2) summary
      cd14719
      Location:639709
      bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
      cd18278
      Location:6129
      BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      32238413..32586109
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011249909.3XP_011248211.1  transcription regulator protein BACH2 isoform X2

      See identical proteins and their annotated locations for XP_011248211.1

      UniProtKB/Swiss-Prot
      P97303
      Related
      ENSMUSP00000103815.3, ENSMUST00000108180.9
      Conserved Domains (2) summary
      cd14719
      Location:639709
      bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
      cd18278
      Location:6129
      BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)
    2. XM_030253112.2XP_030108972.1  transcription regulator protein BACH2 isoform X2

      Conserved Domains (2) summary
      cd14719
      Location:639709
      bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
      cd18278
      Location:6129
      BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)
    3. XM_011249908.4XP_011248210.1  transcription regulator protein BACH2 isoform X1

      See identical proteins and their annotated locations for XP_011248210.1

      Conserved Domains (2) summary
      cd14719
      Location:646716
      bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
      cd18278
      Location:13136
      BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)
    4. XM_006537566.5XP_006537629.1  transcription regulator protein BACH2 isoform X1

      See identical proteins and their annotated locations for XP_006537629.1

      Conserved Domains (2) summary
      cd14719
      Location:646716
      bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
      cd18278
      Location:13136
      BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)
    5. XM_030253109.2XP_030108969.1  transcription regulator protein BACH2 isoform X1

      Conserved Domains (2) summary
      cd14719
      Location:646716
      bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
      cd18278
      Location:13136
      BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)
    6. XM_036163607.1XP_036019500.1  transcription regulator protein BACH2 isoform X2

      Conserved Domains (2) summary
      cd14719
      Location:639709
      bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
      cd18278
      Location:6129
      BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)
    7. XM_036163608.1XP_036019501.1  transcription regulator protein BACH2 isoform X2

      Conserved Domains (2) summary
      cd14719
      Location:639709
      bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
      cd18278
      Location:6129
      BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)
    8. XM_006537567.5XP_006537630.1  transcription regulator protein BACH2 isoform X2

      See identical proteins and their annotated locations for XP_006537630.1

      UniProtKB/Swiss-Prot
      P97303
      Conserved Domains (2) summary
      cd14719
      Location:639709
      bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain
      cd18278
      Location:6129
      BTB_POZ_BACH2; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in BTB and CNC homolog 2 (BACH2)
    9. XM_011249910.4XP_011248212.1  transcription regulator protein BACH2 isoform X3

      Conserved Domains (1) summary
      cd14719
      Location:522592
      bZIP_BACH; Basic leucine zipper (bZIP) domain of BTB and CNC homolog (BACH) proteins: a DNA-binding and dimerization domain

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_007521.3: Suppressed sequence

      Description
      NM_007521.3: This RefSeq was permanently suppressed because it represents a poorly supported variant with non-consensus splice sites.
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